Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management.

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第一作者： Marta,López-Nevado

第一单位： Immunology Department, University Hospital 12 de Octubre, Madrid, Spain.;Research Institute Hospital 12 Octubre (imas12), Madrid, Spain.

作者： Marta,López-Nevado ^[1] ; Luis I,González-Granado ^[2] ; Raquel,Ruiz-García ^[3] ; Daniel,Pleguezuelo ^[1] ; Oscar,Cabrera-Marante ^[1] ; Nerea,Salmón ^[2] ; Pilar,Blanco-Lobo ^[4] ; Nerea,Domínguez-Pinilla ^[5] ; Rebeca,Rodríguez-Pena ^[6] ; Elena,Sebastián ^[7] ; Jaime,Cruz-Rojo ^[8] ; Peter,Olbrich ^[4] ; Jesús,Ruiz-Contreras ^[9] ; Estela,Paz-Artal ^[10] ; Olaf,Neth ^[4] ; Luis M,Allende ^[10]

作者单位： Immunology Department, University Hospital 12 de Octubre, Madrid, Spain.;Research Institute Hospital 12 Octubre (imas12), Madrid, Spain. ^[1] Research Institute Hospital 12 Octubre (imas12), Madrid, Spain.;Immunodeficiency Unit, Department of Pediatrics, University Hospital 12 de Octubre, Madrid, Spain. ^[2] Immunology Department, Centre Diagnòstic Biomèdic, Hospital Clínic, Barcelona, Spain. ^[3] Paediatric Infectious Diseases, Rheumatology and Immunology Unit, University Hospital Virgen del Rocío, Institute of Biomedicine, Biomedicine Institute (IBiS)/University of Seville/Superior Council of Scientific Investigations (CSIC), Seville, Spain. ^[4] Research Institute Hospital 12 Octubre (imas12), Madrid, Spain.;Pediatric Hematology and Oncology Unit, Toledo Hospital Complex, Toledo, Spain and University Hospital 12 de Octubre, Madrid, Spain. ^[5] Immunology Department, University Hospital La Paz, Madrid, Spain. ^[6] Hematology and Hemotherapy Unit, University Children's Hospital Niño Jesús, Madrid, Spain. ^[7] Endocrine Unit, Department of Pediatrics, University Hospital 12 de Octubre, Madrid, Spain. ^[8] Research Institute Hospital 12 Octubre (imas12), Madrid, Spain.;Immunodeficiency Unit, Department of Pediatrics, University Hospital 12 de Octubre, Madrid, Spain.;School of Medicine, Complutense University of Madrid, Madrid, Spain. ^[9] Immunology Department, University Hospital 12 de Octubre, Madrid, Spain.;Research Institute Hospital 12 Octubre (imas12), Madrid, Spain.;School of Medicine, Complutense University of Madrid, Madrid, Spain. ^[10]

关键词 ALPS ALPS-like autoimmunity immune dysregulation lymphoproliferation malignancy

主题词自身免疫性淋巴细胞增生综合征(Autoimmune Lymphoproliferative Syndrome);早期诊断(Early Diagnosis);人类(Humans)

DOI 10.3389/fimmu.2021.671755

PMID 34447369

发布时间 2024-12-05

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