Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases.

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作者： Panpan,Hou ^[1] ; Yuxin,Lin ^[1] ; Zibo,Li ^[1] ; Ruiqing,Lu ^[1] ; Yicheng,Wang ^[1] ; Tian,Tian ^[2] ; Penghui,Jia ^[1] ; Xi,Zhang ^[3] ; Liu,Cao ^[1] ; Zhongwei,Zhou ^[1] ; Chunmei,Li ^[1] ; Jieruo,Gu ^[3] ; Deyin,Guo ^[4]

作者单位： MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University, Shenzhen, China. ^[1] The Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. ^[2] Division of Rheumatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[3] MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University, Shenzhen, China. guodeyin@mail.sysu.edu.cn. ^[4]

关键词 Autoimmune diseases Autophagy CCDC50 HSV-1 STING Type I IFN

主题词动物(Animals);自身免疫疾病(Autoimmune Diseases);自噬(Autophagy);人类(Humans);免疫, 先天(Immunity, Innate);干扰素Ⅰ型(Interferon Type I);干扰素类(Interferons);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);病毒性疾病(Virus Diseases)

DOI 10.1038/s41423-021-00758-w

PMID 34453126

发布时间 2023-02-05

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Cellular & molecular immunology

2021年18卷10期

2358-2371页

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Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases.

Cellular & molecular immunology

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Cellular & molecular immunology

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Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases.

Cellular & molecular immunology

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Cellular & molecular immunology

相关期刊

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