The histone methyltransferase Ezh2 restrains macrophage inflammatory responses.

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第一作者： Gareth B,Kitchen

第一单位： Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.

作者： Gareth B,Kitchen ^[1] ; Thomas,Hopwood ^[2] ; Thanuja,Gali Ramamoorthy ^[1] ; Polly,Downton ^[1] ; Nicola,Begley ^[1] ; Tracy,Hussell ^[1] ; David H,Dockrell ^[1] ; Julie E,Gibbs ^[3] ; David W,Ray ^[1] ; Andrew S I,Loudon ^[4]

作者单位： Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK. ^[1] Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. ^[2] Department of Infection Medicine and MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK. ^[3] NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK. ^[4] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. ^[5]

关键词 EZHZ inflammation lung macrophage neutrophil

主题词动物(Animals);细胞, 培养的(Cells, Cultured);炎症(Inflammation);巨噬细胞(Macrophages);小鼠, 近交C57BL(Mice, Inbred C57BL);中性白细胞(Neutrophils);小鼠(Mice)

DOI 10.1096/fj.202100044RRR

PMID 34464475

发布时间 2024-03-06

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