DUSP6 expression is associated with osteoporosis through the regulation of osteoclast differentiation via ERK2/Smad2 signaling.
第一作者:
Boya,Zhang
第一单位:
Department of Dermatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.;Key Laboratory of Biotherapy of Zhejiang Province, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
作者:
医学主题词
动物(Animals);骨质吸收(Bone Resorption);骨和骨组织(Bone and Bones);细胞分化(Cell Differentiation);疾病模型, 动物(Disease Models, Animal);减量调节(Down-Regulation);双特异性磷酸酶6(Dual Specificity Phosphatase 6);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);人类(Humans);巨噬细胞(Macrophages);小鼠, 近交C57BL(Mice, Inbred C57BL);破骨细胞(Osteoclasts);骨生成(Osteogenesis);骨质疏松(Osteoporosis);RANK配体(RANK Ligand);信号传导(Signal Transduction);Smad2蛋白质(Smad2 Protein);小鼠(Mice)
DOI
10.1038/s41419-021-04110-y
PMID
34475393
发布时间
2024-02-26
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