Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes.

导出 OA

翻译打印收藏纠错

第一作者： Ahmed,El-Boraie

第一单位： Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON, Canada.

作者： Ahmed,El-Boraie ^[1] ; Julie-Anne,Tanner ^[2] ; Andy Z X,Zhu ^[3] ; Katrina G,Claw ^[4] ; Bhagwat,Prasad ^[5] ; Erin G,Schuetz ^[6] ; Kenneth E,Thummel ^[7] ; Koya,Fukunaga ^[8] ; Taisei,Mushiroda ^[9] ; Michiaki,Kubo ^[9] ; Neal L,Benowitz ^[9] ; Caryn,Lerman ^[10] ; Rachel F,Tyndale ^[11]

作者单位： Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON, Canada. ^[1] Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health and Division of Brain and Therapeutics, Toronto, ON, Canada. ^[2] Myriad Neuroscience, Toronto, ON, Canada. ^[3] Department of Quantitative Translational Sciences, Takeda Pharmaceuticals, Cambridge, Massachusetts, USA. ^[4] Division of Biomedical Informatics and Personalized Medicine, University of Colorado, Aurora, Colorado, USA. ^[5] Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA. ^[6] Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. ^[7] Department of Pharmaceutics, University of Washington, Seattle, Washington, USA. ^[8] Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan. ^[9] Clinical Pharmacology Research Program, Division of Cardiology, Department of Medicine and Center for Tobacco Control Research and Education, University of California San Francisco, San Francisco, California, USA. ^[10] Department of Psychiatry, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. ^[11] Department of Psychiatry, University of Toronto, Toronto, ON, Canada. ^[12]