Quality of life after simultaneously integrated boost with intensity-modulated versus conventional radiotherapy with sequential boost for adjuvant treatment of breast cancer: 2-year results of the multicenter randomized IMRT-MC2 trial.

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第一作者： Tobias,Forster

第一单位： Department of Radiation Oncology, Heidelberg University Hospital, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Germany; National Center for Tumor Diseases (NCT), Heidelberg, Germany.

作者： Tobias,Forster ^[1] ; Adriane,Hommertgen ^[1] ; Matthias Felix,Häfner ^[1] ; Nathalie,Arians ^[1] ; Laila,König ^[1] ; Semi Ben,Harrabi ^[1] ; Ingmar,Schlampp ^[1] ; Clara,Köhler ^[2] ; Eva,Meixner ^[1] ; Vanessa,Heinrich ^[3] ; Nicola,Weidner ^[3] ; Johannes,Hüsing ^[4] ; Christof,Sohn ^[5] ; Jörg,Heil ^[5] ; Michael,Golatta ^[5] ; Holger,Hof ^[6] ; David,Krug ^[7] ; Jürgen,Debus ^[8] ; Juliane,Hörner-Rieber ^[9]

作者单位： Department of Radiation Oncology, Heidelberg University Hospital, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Germany; National Center for Tumor Diseases (NCT), Heidelberg, Germany. ^[1] Department of Radiation Oncology, Heidelberg University Hospital, Germany. ^[2] Department of Radiation Oncology, Eberhard-Karls-University Tuebingen, Germany. ^[3] Division of Biostatistics, Coordination Centre for Clinical Trials, University of Heidelberg, Germany. ^[4] Department of Gynecology and Obstetrics, University of Heidelberg, Germany. ^[5] Strahlentherapie Rhein-Pfalz, Neustadt, Germany. ^[6] Department of Radiation Oncology, Heidelberg University Hospital, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Germany; National Center for Tumor Diseases (NCT), Heidelberg, Germany; Department of Radiation Oncology, University Hospital Schleswig Holstein, Kiel, Germany. ^[7] Department of Radiation Oncology, Heidelberg University Hospital, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Germany; National Center for Tumor Diseases (NCT), Heidelberg, Germany; Department of Radiation Oncology, University Hospital Schleswig Holstein, Kiel, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Germany. ^[8] Department of Radiation Oncology, Heidelberg University Hospital, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Germany; National Center for Tumor Diseases (NCT), Heidelberg, Germany; Department of Radiation Oncology, University Hospital Schleswig Holstein, Kiel, Germany; German Cancer Consortium (DKTK), partner site, Heidelberg, Germany. Electronic address: juliane.hoerner-rieber@med.uni-heidelberg.de. ^[9]

关键词 3-D-conformal radiotherapy Breast cancer Intensity-modulated radiotherapy (IMRT)Quality of life Sequential boost irradiation Simultaneously integrated boost (SIB)