Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes.
第一作者:
Liam,Simms
第一单位:
Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL UK.
作者:
关键词
ACM, aerosol collected massAhR, Aryl hydrocarbon receptorAlternative methodsCOPD, Chronic obstructive pulmonary diseaseEGFR, epidermal growth factor receptorELISA, enzyme-linked immunosorbent assayEVP, Electronic vapor productHDFn, Human neonatal dermal fibroblastsHTP, Heated Tobacco ProductHUVEC, Human umbilical vein endothelial cellsHYB, Hybrid product containing e-liquid drawn through a tobacco plugIL, interleukinISO, International Organization for StandardizationIn vitro assaysMOA, Mechanism of actionM?CSF, Macrophage colony-stimulating factorNGP, Next generation productNRC, National Research CouncilNRF2, Nuclear factor erythroid 2-related factor 2Next generation productsPBMC, Peripheral blood mononuclear cellsPBS, Phosphate buffered salinePanelPhenotypic screeningSRB, Sulforhodamine BTCR, T cell receptorTF, Tissue factorTLR, toll-like receptorTNFα, tumor necrosis factor alphaTPM, Total particulate matterToxicity signaturebPBS, Bubbled phosphate buffered salinemTOR, mechanistic target of rapamycin
DOI
10.1016/j.crtox.2021.08.003
PMID
34485931
发布时间
2024-04-03
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Current research in toxicology
2021年2卷
309-321页
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