Epigenetic clock and methylation studies in the rhesus macaque.

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作者： Steve,Horvath ^[1] ; Joseph A,Zoller ^[2] ; Amin,Haghani ^[2] ; Anna J,Jasinska ^[1] ; Ken,Raj ^[3] ; Charles E,Breeze ^[4] ; Jason,Ernst ^[5] ; Kelli L,Vaughan ^[6] ; Julie A,Mattison ^[7]

作者单位： Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. ^[1] Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA. ^[2] Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, Los Angeles, USA. ^[3] Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, , Didcot, UK. ^[4] Altius Institute for Biomedical Sciences, Seattle, WA, USA. ^[5] Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ^[6] Translational Gerontology Branch, National Institute on Aging Intramural Research Program, National Institutes of Health, 16701 Elmer School Rd., MD, 20842, Dickerson, USA. ^[7] Translational Gerontology Branch, National Institute on Aging Intramural Research Program, National Institutes of Health, 16701 Elmer School Rd., MD, 20842, Dickerson, USA. Julie.mattison@nih.gov. ^[8]

关键词 DNA methylation Epigenetic clock Nonhuman primate Rhesus monkey

主题词衰老(Aging);动物(Animals);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);表观基因组学(Epigenomics);猕猴(Macaca mulatta);启动区, 遗传(Promoter Regions, Genetic)

DOI 10.1007/s11357-021-00429-8

PMID 34487267

发布时间 2024-04-04

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2021年43卷5期

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Epigenetic clock and methylation studies in the rhesus macaque.

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Epigenetic clock and methylation studies in the rhesus macaque.

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