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首页> Life sciences> RNA-seq reveal RNA binding protein GNL3 as a key mediator in the development of psoriasis vulgaris by regulating the IL23/IL17 axis.

RNA-seq reveal RNA binding protein GNL3 as a key mediator in the development of psoriasis vulgaris by regulating the IL23/IL17 axis.

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作者： Xiaomin,Yao ^[1] ; Zhen,Zhu ^[2] ; Upasana,Manandhar ^[1] ; Han,Liao ^[3] ; Tiexi,Yu ^[2] ; Yueying,Wang ^[1] ; Yawen,Bian ^[1] ; Bo,Zhang ^[2] ; Xuanhong,Zhang ^[4] ; Jun,Xie ^[5] ; Jiquan,Song ^[6]

作者单位： Deparment of Dermatology, Zhongnan Hospital, Wuhan University, China. ^[1] Department of orthopedics, Wuhan Union Hospital, Huazhong University of Science and Technology, China. ^[2] Laboratory of General Surgery Department, Wuhan Union Hospital, Huazhong University of Science and Technology, China. ^[3] Department of Pathology, Lujiang County Hospital of Traditional Chinese Medicine Hospital, Hefei, Anhui, China. ^[4] Deparment of Dermatology, Zhongnan Hospital, Wuhan University, China. Electronic address: xiejunz@sina.com. ^[5] Deparment of Dermatology, Zhongnan Hospital, Wuhan University, China. Electronic address: songjiq@126.com. ^[6]

关键词 GNL3 IL23A Psoriasis vulgaris RNA binding protein TNFAIP3

主题词细胞系, 转化(Cell Line, Transformed);GTP结合蛋白质类(GTP-Binding Proteins);人类(Humans);白细胞介素17(Interleukin-17);白细胞介素23(Interleukin-23);角蛋白细胞(Keratinocytes);核蛋白质类(Nuclear Proteins);银屑病(Psoriasis);RNA结合蛋白质类(RNA-Binding Proteins)

DOI 10.1016/j.lfs.2021.119902

PMID 34487784

发布时间 2022-02-21

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