Real-world particulate matters induce lung toxicity in rats fed with a high-fat diet: Evidence of histone modifications.

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第一作者： Xuejingping,Han

第一单位： Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; University of Chinese Academy of Sciences, Beijing 100049, China.

作者： Xuejingping,Han ^[1] ; Meiping,Tian ^[2] ; Pavel V,Shliaha ^[3] ; Jie,Zhang ^[4] ; Shoufang,Jiang ^[5] ; Bingru,Nan ^[1] ; Md Nur,Alam ^[1] ; Ole N,Jensen ^[6] ; Heqing,Shen ^[7] ; Qingyu,Huang ^[8]

作者单位： Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; University of Chinese Academy of Sciences, Beijing 100049, China. ^[1] Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China. ^[2] Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark. ^[3] State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-117 Xiang An Nan Road, Xiamen 361102, China. Electronic address: jie.zhang@xmu.edu.cn. ^[4] Department of Occupational and Environmental Health, School of Public Health, North China University of Science and Technology, Tangshan 063000, China. ^[5] Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark. Electronic address: jenseno@bmb.sdu.dk. ^[6] State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-117 Xiang An Nan Road, Xiamen 361102, China. ^[7] Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China. Electronic address: qyhuang@iue.ac.cn. ^[8]

关键词 DNA damage High-fat diet Histone modifications Lung toxicity Real-world PM exposure