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Sensory nerves: A driver of the vicious cycle in bone metastasis?

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第一作者: Toshiyuki,Yoneda
第一单位: Department of Biochemistry, Osaka University Graduate School of Dentistry, Osaka, Japan.
作者: Toshiyuki,Yoneda [1] ; Masahiro,Hiasa [2] ; Tatsuo,Okui [3] ; Kenji,Hata [1]
作者单位: Department of Biochemistry, Osaka University Graduate School of Dentistry, Osaka, Japan. [1] Department of Biomaterials and Bioengineerings, University of Tokushima Graduate School of Dentistry, Tokushima, Japan. [2] Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan. [3]
关键词 AN, autonomic nerveBDNF, brain-derived neurotrophic factorBMP, bone morphogenetic proteinBMSC, bone marrow stromal cellsBone microenvironmentCABP, cancer-associated bone painCALCRL, calcitonin receptor-like receptorCAP, cancer-associated painCCL2, C–C motif chemokine 2CGRP, calcitonin gene-related peptideCNS, central nervous systemCOX, cyclooxygenaseCREB, cyclic AMP-responsive element-binding proteinCRPC, castration-resistant prostate cancerCXCL1, C-X-C Motif Chemokine Ligand 1CXCL2, C-X-C Motif Chemokine Ligand 2Cancer-associated bone painDRG, dorsal root ganglionERK1/2, extracellular receptor kinase ?G-CSF, granulocyte colony-stimulating factorGDNF, glial-derived neurotrophic factorHGF, hepatocyte growth factorHIF-1α, hypoxia-inducible transcription factor-1αHMGB-1, high mobility group box-1HSCs, hematopoietic stem cellsHUVECs, human umbilical vein endothelial cellsIL-1β, interleukin 1βMM, multiple myelomaMOR, mu-opioid receptorNE, norepinephrineNGF, nerve growth factorNI, nerve invasionNPY, neuropeptide YNSAIDs, nonsteroidal anti-inflammatory drugsNociceptorsOA, osteoarthritisOPG, osteoprotegerinPACAP, pituitary adenylate cyclase-activating peptidePD-1, programmed cell death-1PD-L1, programmed death-ligand 1PDAC, pancreatic ductal adenocarcinomaPGE2, prostaglandin E2PNI, perineural invasionPanIN, pancreatic intraepithelial neoplasiaPerineural invasionRAGE, receptor for advanced glycation end productsRAMP1, receptor activity modifying protein 1RANKL, receptor activator of NF-κB ligandRTX, resiniferatoxinSN, sensory nervesSP, substance PSRE, skeletal-related eventSensory nervesTGFβ, transforming growth factor βTNFα, tumor necrosis factor αTRPV1TrkA, tyrosine kinase receptor type 1VEGF, vascular endothelial growth factorVIP, vasoactive intestinal peptidea3V-H+-ATPase, a3 isoform vacuolar proton pump
DOI 10.1016/j.jbo.2021.100387
PMID 34504741
发布时间 2023-11-07
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Journal of bone oncology

Journal of bone oncology

2021年30卷

100387页

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