A Platform for Deep Sequence-Activity Mapping and Engineering Antimicrobial Peptides.

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作者： Matthew P,DeJong ^[1] ; Seth C,Ritter ^[1] ; Katharina A,Fransen ^[1] ; Daniel T,Tresnak ^[1] ; Alexander W,Golinski ^[1] ; Benjamin J,Hackel ^[1]

作者单位： Department of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, Minneapolis, Minnesota 55455, United States. ^[1]

关键词 antimicrobial peptide deep mutational scanning oncocin protein engineering ribosome

主题词抗菌药(Anti-Bacterial Agents);大肠杆菌(Escherichia coli);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);微生物敏感性试验(Microbial Sensitivity Tests);蛋白质工程(Protein Engineering)

DOI 10.1021/acssynbio.1c00314

PMID 34506711

发布时间 2022-10-16

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