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Bedside testing of CYP2C19 vs. conventional clopidogrel treatment to guide antiplatelet therapy in ST-segment elevation myocardial infarction patients.

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第一作者： Abdullah M,Al-Rubaish

第一单位： Department of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

作者： Abdullah M,Al-Rubaish ^[1] ; Fahad A,Al-Muhanna ^[1] ; Abdullah M,Alshehri ^[1] ; Mohammed A,Al-Mansori ^[1] ; Rudaynah A,Alali ^[1] ; Rania M,Khalil ^[1] ; Khalid A,Al-Faraidy ^[2] ; Cyril,Cyrus ^[3] ; Mohammed M,Sulieman ^[1] ; Chittibabu,Vatte ^[3] ; Bao-Li,Loza ^[4] ; Daniel M F,Claassens ^[5] ; Folkert W,Asselbergs ^[6] ; Amein K,Al-Ali ^[7]

作者单位： Department of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. ^[1] Department of Cardiology, King Fahd Armed Forces Hospital, Dhahran, Saudi Arabia. ^[2] Department of Clinical Biochemistry, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia. ^[3] Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ^[4] Department of Cardiology, Isala Klinieken, Zwolle, the Netherlands. ^[5] Department of Cardiology, University Medical Center Utrecht, ICIN-Netherlands Heart Institute, Durrer Centre for Cardiogenetic Research, Utrecht, the Netherlands; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK. ^[6] Department of Clinical Biochemistry, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia. Electronic address: aalali@iau.edu.sa. ^[7]

关键词 CYP2C19 Clopidogrel P2Y12 inhibitor PCI STEMI Ticagrelor

医学主题词人类(Humans);心肌梗死(Myocardial Infarction);血小板聚集抑制剂(Platelet Aggregation Inhibitors);前瞻性研究(Prospective Studies);治疗结果(Treatment Outcome)

DOI 10.1016/j.ijcard.2021.08.051

PMID 34506827

发布时间 2021-11-24

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