Formalin RT-QuIC assay detects prion-seeding activity in formalin-fixed brain samples from sporadic Creutzfeldt-Jakob disease patients.

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第一作者： Thi-Thu-Trang,Dong

第一单位： Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Japan.

作者： Thi-Thu-Trang,Dong ^[1] ; Akio,Akagi ^[2] ; Toshiaki,Nonaka ^[3] ; Takehiro,Nakagaki ^[4] ; Ban,Mihara ^[5] ; Masaki,Takao ^[6] ; Yasushi,Iwasaki ^[7] ; Noriyuki,Nishida ^[4] ; Katsuya,Satoh ^[8]

作者单位： Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Japan. ^[1] Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Aichi 480-1195, Japan. ^[2] Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Japan; Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan. ^[3] Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan. ^[4] Department of Neurology, Institute of Brain and Blood Vessels, Mihara Memorial Hospital, Isesaki 372-0006, Japan. Electronic address: ban.mihara@mihara-ibbv.jp. ^[5] Department of Neurology, Institute of Brain and Blood Vessels, Mihara Memorial Hospital, Isesaki 372-0006, Japan; Department of Neurology International Medical Center, Saitama Medical University, Saitama 350-1298, Japan; Department of Clinical Laboratory National Center of Neurology and Psychiatry (NCNP), National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira, Tokyo 187-8551, Japan. ^[6] Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Aichi 480-1195, Japan. Electronic address: iwasaki@sc4.so-net.ne.jp. ^[7] Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Japan. Electronic address: satoh-prion@nagasaki-u.ac.jp. ^[8]

关键词 Neuropathology Prion Prion-seeding activity RT-QUIC assay