换一批
换一批Development of pteridin-7(8H)-one analogues as highly potent cyclin-dependent kinase 4/6 inhibitors: Synthesis, structure-activity relationship, and biological activity.
第一作者：
Qiu,Li
第一单位：
Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, PR China.
作者：
主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞周期(Cell Cycle);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞周期蛋白依赖激酶4(Cyclin-Dependent Kinase 4);细胞周期蛋白依赖激酶6(Cyclin-Dependent Kinase 6);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);分子结构(Molecular Structure);蛋白激酶抑制剂(Protein Kinase Inhibitors);蝶啶类(Pteridines);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bioorg.2021.105324
PMID
34509794
发布时间
2021-12-20
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Bioorganic chemistry
105324页
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