B cell depletion with anti-CD20 mAb exacerbates anti-donor CD4<sup>+</sup> T cell responses in highly sensitized transplant recipients.-论文-万方医学网

作者： Asuka,Tanaka ^[1] ; Kentaro,Ide ^[2] ; Yuka,Tanaka ^[1] ; Masahiro,Ohira ^[1] ; Hiroyuki,Tahara ^[1] ; Hideki,Ohdan ^[3]

作者单位： Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima, 734-8551, Japan. ^[1] Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima, 734-8551, Japan. ideken@hiroshima-u.ac.jp. ^[2] Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima, 734-8551, Japan. hohdan@hiroshima-u.ac.jp. ^[3]

主题词成年人(Adult);老年人(Aged);动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗原, CD20(Antigens, CD20);B-淋巴细胞(B-Lymphocytes);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);移植物存活(Graft Survival);组织相容性试验(Histocompatibility Testing);人类(Humans);免疫(Immunity);免疫法(Immunization);动力学(Kinetics);淋巴细胞去除术(Lymphocyte Depletion);淋巴细胞亚群(Lymphocyte Subsets);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);中年人(Middle Aged);青年人(Young Adult);小鼠(Mice)

DOI 10.1038/s41598-021-97748-9

PMID 34518640

发布时间 2024-02-26

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B cell depletion with anti-CD20 mAb exacerbates anti-donor CD4<sup>+</sup> T cell responses in highly sensitized transplant recipients.

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B cell depletion with anti-CD20 mAb exacerbates anti-donor CD4<sup>+</sup> T cell responses in highly sensitized transplant recipients.

Scientific reports

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Scientific reports

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