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Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone.

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第一作者： Nathalie,Diener

第一单位： Institute for Molecular Medicine, Paul Klein Center for Immune Intervention, University Medical Center of the Johannes Gutenberg-University, 55131 Mainz, Germany.

作者： Nathalie,Diener ^[1] ; Jean-Fred,Fontaine ^[2] ; Matthias,Klein ^[3] ; Thomas,Hieronymus ^[4] ; Florian,Wanke ^[1] ; Florian C,Kurschus ^[1] ; Andreas,Ludwig ^[5] ; Carl,Ware ^[6] ; Paul,Saftig ^[7] ; Tobias,Bopp ^[3] ; Björn E,Clausen ^[8] ; Ronald A,Backer ^[8]

作者单位： Institute for Molecular Medicine, Paul Klein Center for Immune Intervention, University Medical Center of the Johannes Gutenberg-University, 55131 Mainz, Germany. ^[1] iOME Computational Biology and Data Mining, Johannes Gutenberg-University, 55128 Mainz, Germany. ^[2] Institute for Immunology, Paul Klein Center for Immune Intervention, University Medical Center of the Johannes Gutenberg-University, 55131 Mainz, Germany.;Research Center for Immunotherapy, University Medical Center of the Johannes Gutenberg-University, 55131 Mainz, Germany. ^[3] Department of Cell Biology, Institute for Biomedical Engineering, Rheinisch-Westfälische Technische Hochschule Aachen, University Medical Center, 52074 Aachen, Germany. ^[4] Institute of Pharmacology and Toxicology, Rheinisch-Westfälische Technische Hochschule Aachen, University Medical Center, 52074 Aachen, Germany. ^[5] Infectious and Inflammatory Diseases Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037. ^[6] Institute of Biochemistry, Christian-Albrechts-University Kiel, 24098 Kiel, Germany. ^[7] Institute for Molecular Medicine, Paul Klein Center for Immune Intervention, University Medical Center of the Johannes Gutenberg-University, 55131 Mainz, Germany; bclausen@uni-mainz.de r.backer@uni-mainz.de.;Research Center for Immunotherapy, University Medical Center of the Johannes Gutenberg-University, 55131 Mainz, Germany. ^[8]

关键词 A-disintegrin-and-metalloproteinase 10 Notch signaling conventional dendritic cells marginal metallophilic macrophages splenic marginal zone