Passive and iontophoretic transport of pramipexole dihydrochloride across human skin microchannels created by microneedles in vitro.

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作者： Kamchai,Saepang ^[1] ; S Kevin,Li ^[2] ; Doungdaw,Chantasart ^[3]

作者单位： Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. ^[1] Division of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267, USA. ^[2] Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. Electronic address: doungdaw.cha@mahidol.ac.th. ^[3]

关键词 Iontophoresis Microchannels Microneedles Pramipexole Transdermal drug delivery

主题词投药, 皮肤(Administration, Cutaneous);药物释放系统(Drug Delivery Systems);人类(Humans);离子透入法(Iontophoresis);针(Needles);皮肤(Skin)

DOI 10.1016/j.ijpharm.2021.121092

PMID 34530098

发布时间 2021-11-09

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