换一批Natalizumab Versus Fingolimod in Patients with Relapsing-Remitting Multiple Sclerosis: A Subgroup Analysis From Three International Cohorts.
第一作者：
Sifat,Sharmin
第一单位：
CORe, Department of Medicine, University of Melbourne, L4 East, Grattan St, Melbourne, VIC, 3050, Australia.
作者：
Sifat,Sharmin [1]
;
Mathilde,Lefort [2]
;
Johanna Balslev,Andersen [3]
;
Emmanuelle,Leray [2]
;
Dana,Horakova [4]
;
Eva Kubala,Havrdova [4]
;
Raed,Alroughani [5]
;
Guillermo,Izquierdo [6]
;
Serkan,Ozakbas [7]
;
Francesco,Patti [8]
;
Marco,Onofrj [9]
;
Alessandra,Lugaresi [10]
;
Murat,Terzi [11]
;
Pierre,Grammond [12]
;
Francois,Grand'Maison [13]
;
Bassem,Yamout [14]
;
Alexandre,Prat [15]
;
Marc,Girard [15]
;
Pierre,Duquette [15]
;
Cavit,Boz [16]
;
Maria,Trojano [17]
;
Pamela,McCombe [18]
;
Mark,Slee [19]
;
Jeannette,Lechner-Scott [20]
;
Recai,Turkoglu [21]
;
Patrizia,Sola [22]
;
Diana,Ferraro [22]
;
Franco,Granella [23]
;
Julie,Prevost [24]
;
Davide,Maimone [25]
;
Olga,Skibina [26]
;
Katherine,Buzzard [27]
;
Anneke,Van der Walt [27]
;
Bart,Van Wijmeersch [28]
;
Tunde,Csepany [29]
;
Daniele,Spitaleri [30]
;
Steve,Vucic [31]
;
Romain,Casey [32]
;
Marc,Debouverie [33]
;
Gilles,Edan [34]
;
Jonathan,Ciron [35]
;
Aurélie,Ruet [36]
;
Jérôme,De Sèze [37]
;
Elisabeth,Maillart [38]
;
Hélène,Zephir [39]
;
Pierre,Labauge [40]
;
Gilles,Defer [41]
;
Christine,Lebrun-Frénay [42]
;
Thibault,Moreau [43]
;
Eric,Berger [44]
;
Pierre,Clavelou [45]
;
Jean,Pelletier [46]
;
Bruno,Stankoff [47]
;
Olivier,Gout [48]
;
Eric,Thouvenot [49]
;
Olivier,Heinzlef [50]
;
Abullatif,Al-Khedr [51]
;
Bertrand,Bourre [52]
;
Olivier,Casez [53]
;
Philippe,Cabre [54]
;
Alexis,Montcuquet [55]
;
Abir,Wahab [56]
;
Jean-Philippe,Camdessanché [57]
;
Aude,Maurousset [58]
;
Ivania,Patry [59]
;
Karolina,Hankiewicz [60]
;
Corinne,Pottier [61]
;
Nicolas,Maubeuge [62]
;
Céline,Labeyrie [63]
;
Chantal,Nifle [64]
;
David,Laplaud [65]
;
Niels,Koch-Henriksen [66]
;
Finn Thorup,Sellebjerg [67]
;
Per Soelberg,Soerensen [67]
;
Claudia Christina,Pfleger [68]
;
Peter Vestergaard,Rasmussen [69]
;
Michael Broksgaard,Jensen [70]
;
Jette Lautrup,Frederiksen [71]
;
Stephan,Bramow [72]
;
Henrik Kahr,Mathiesen [73]
;
Karen Ingrid,Schreiber [67]
;
Melinda,Magyari [74]
;
Sandra,Vukusic [75]
;
Helmut,Butzkueven [76]
;
Tomas,Kalincik [77]
;
Danish Multiple Sclerosis Registry, OFSEP and the MSBase investigators
作者单位：
CORe, Department of Medicine, University of Melbourne, L4 East, Grattan St, Melbourne, VIC, 3050, Australia.
[1]
Rennes University, EHESP, REPERES, EA, 7449, Rennes, France.;Univ Rennes, CHU Rennes, Inserm, CIC 1414 (Centre d'Investigation Clinique de Rennes), Rennes, France.
[2]
The Danish Multiple Sclerosis Registry, Department of Neurology, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.
[3]
Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic.
[4]
Division of Neurology, Department of Medicine, Amiri Hospital, Sharq, Kuwait.
[5]
Hospital Universitario Virgen Macarena, Seville, Spain.
[6]
Dokuz Eylul University, Konak, Izmir, Turkey.
[7]
Department of Medical and Surgical Sciences and Advanced Technologies, GF Ingrassia, Catania, Italy.;Multiple Sclerosis Center, University of Catania, Catania, Italy.
[8]
Department of Neuroscience, Imaging, and Clinical Sciences, University G. d'Annunzio, Chieti, Italy.
[9]
IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.;Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italia.
[10]
Medical Faculty, 19 Mayis University, Samsun, Turkey.
[11]
CISSS Chaudière-Appalache, Levis, Canada.
[12]
Neuro Rive-Sud, Greenfield Park, Quebec, Canada.
[13]
Nehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Beirut, Lebanon.
[14]
CHUM MS Center and Universite de Montreal, Montreal, Canada.
[15]
KTU Medical Faculty Farabi Hospital, Trabzon, Turkey.
[16]
Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari, Bari, Italy.
[17]
University of Queensland, Brisbane, Australia.;Royal Brisbane and Women's Hospital, Brisbane, Australia.
[18]
College of Medicine and Public Health, Flinders University, Adelaide, Australia.
[19]
School of Medicine and Public Health, University Newcastle, Newcastle, Australia.;Department of Neurology, John Hunter Hospital, Hunter New England Health, Newcastle, Australia.
[20]
Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
[21]
Department of Neuroscience, Azienda Ospedaliera Universitaria, Modena, Italy.
[22]
Department of Medicine and Surgery, University of Parma, Parma, Italy.;Department of Emergency and General Medicine, Parma University Hospital, Parma, Italy.
[23]
CSSS Saint-Jérôme, Saint-Jerome, Canada.
[24]
Neurology Unit, Garibaldi Hospital, Catania, Italy.
[25]
Department of Neuroscience, Monash University, Melbourne, Australia.;Department of Neurology, The Alfred Hospital, Melbourne, Australia.
[26]
Department of Neurology, The Alfred Hospital, Melbourne, Australia.;Central Clinical School, Monash University, Melbourne, Australia.
[27]
Rehabilitation and MS-Centre Overpelt and Hasselt University, Hasselt, Belgium.
[28]
Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
[29]
Azienda Ospedaliera di Rilievo Nazionale San Giuseppe Moscati Avellino, Avellino, Italy.
[30]
Neurophysiology Department, Westmead Hospital, Sydney, Australia.
[31]
Université de Lyon, Université, Claude Bernard Lyon 1, F-69000, Lyon, France.;Service de neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, Lyon, France.;Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, 69003, Lyon, France.;EUGENE DEVIC EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, 69677, Bron, France.
[32]
Department of Neurology, Nancy University Hospital, Nancy, France.;Université de Lorraine, APEMAC, 54000, Nancy, France.
[33]
CHU Pontchaillou, CIC1414 INSERM, 35000, Rennes, France.
[34]
Department of Neurology, CHU de Toulouse, Hôpital Pierre-Paul Riquet, CRC-SEP, 31059, Toulouse Cedex 9, France.
[35]
Neurocentre Magendie, Université de Bordeaux, 33000, Bordeaux, France.;INSERM U1215, Neurocentre Magendie, 33000, Bordeaux, France.;Department of Neurology, CHU de Bordeaux, CIC Bordeaux CIC1401, 33000, Bordeaux, France.
[36]
Department of Neurology and Clinical Investigation Center, CHU de Strasbourg, CIC 1434, INSERM 1434, 67000, Strasbourg, France.
[37]
Département de neurologie, Hôpital Pitié-Salpêtrière, APHP, Paris, France.;Centre de Ressources et de Compétences SEP, Paris, France.
[38]
CHU Lille, CRCSEP Lille, Univ Lille, U1172, 59000, Lille, France.
[39]
MS Unit, CHU de Montpellier, 34295, Montpellier Cedex 5, France.;University of Montpellier (MUSE), 34000, Montpellier, France.
[40]
Department of Neurology, CHU de Caen, MS Expert Centre, Normandy University, avenue de la Côte-de-Nacre, 14033, Caen, France.
[41]
CRCSEP Nice, UR2CA, Université Nice Cote d'Azur, Hopital Pasteur2, 06002, Nice, France.
[42]
Department of Neurology, CHU de Dijon, EA4184, 21000, Dijon, France.
[43]
CHU de Besançon, Service de Neurologie 25 030, Besançon, France.
[44]
Department of Neurology, CHU Clermont-Ferrand, 63000, Clermont-Ferrand, France.;Université Clermont Auvergne, Inserm, Neuro-Dol, 63000, Clermont-Ferrand, France.
[45]
Aix Marseille Univ, APHM, Hôpital de la Timone, Pôle de Neurosciences Cliniques, Service de Neurologie, 13005, Marseille, France.
[46]
Sorbonne Universités, UPMC Paris 06, Brain and Spine Institute, ICM, Hôpital de la Pitié Salpêtrière, Inserm UMR S 1127, CNRS UMR 7225, Paris, France.;Department of Neurology, AP-HP, Saint-Antoine Hospital, 75000, Paris, France.
[47]
Department of Neurology, Fondation Rotschild, 75000, Paris, France.
[48]
Department of Neurology, Nimes University Hospital, 30029, Nimes Cedex 9, France.;Institut de Génomique Fonctionnelle, UMR5203, INSERM 1191, Univ. Montpellier, 34094, Montpellier Cedex 5, France.
[49]
Department of Neurology, Hôpital de Poissy, 78300, Poissy, France.
[50]
Department of Neurology, CHU d'Amiens, 80000, Amiens, France.
[51]
Department of Neurology, CHU de Rouen, 76000, Rouen, France.
[52]
Department of Neurology, CHU Grenoble Alpes, La Tronche, 38700, Grenoble, France.
[53]
Department of Neurology, CHU de la Martinique, 97200, Fort-de-France, France.
[54]
Department of Neurology, CHU de Limoges, Hôpital Dupuytren, 87000, Limoges, France.
[55]
Department of Neurology, APHP, Hôpital Henri Mondor, 94000, Créteil, France.
[56]
Department of Neurology, CHU de Saint-Étienne, Hôpital Nord, 42000, Saint-Étienne, France.
[57]
CRC SEP and Department of Neurology, CHU de Tours, Hôpital Bretonneau, 37000, Tours, France.
[58]
Department of Neurology, Hôpital Sud Francilien, 91160, Corbeil Essonnes, France.
[59]
Department of Neurology, Hôpital Pierre Delafontaine, Centre Hospitalier de Saint-Denis, 93200, Saint-Denis, France.
[60]
Department of Neurology, CH de Pontoise, Hôpital René Dubos, 95300, Pontoise, France.
[61]
Department of Neurology, CHU La Milétrie, Hôpital Jean Bernard, 86000, Poitiers, France.
[62]
Department of Neurology, CHU Bicêtre, 94275, Le Kremlin Bicêtre, France.
[63]
Department of Neurology, Centre Hospitalier de Versailles, 78150, Le Chesnay, France.
[64]
CHU de Nantes, Service de Neurologie & CIC015 INSERM, 44093, Nantes, France.;CRTI-Inserm U1064, 44000, Nantes, France.
[65]
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
[66]
Department of Neurology, The Danish Multiple Sclerosis Center, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.
[67]
Multiple Sclerosis Unit, Department of Neurology, Aalborg University Hospital, Aalborg, Denmark.
[68]
Aarhus University Hospital, Neurology, PPJ Boulevard, 8200, Aarhus N, Denmark.
[69]
Department of Neurology, University Hospital of Northern Sealand, Helsingør, Denmark.
[70]
Department of Neurology, Rigshospitalet Glostrup, Copenhagen, Denmark.;Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
[71]
Department of Neurology, Danish Multiple Sclerosis Centre, Copenhagen University Hospital, Rigshospitalet in Glostrup, 2600, Glostrup, Denmark.
[72]
Department of Neurology, Copenhagen University Hospital Herlev, Herlev, Denmark.
[73]
The Danish Multiple Sclerosis Registry, Department of Neurology, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.;Department of Neurology, The Danish Multiple Sclerosis Center, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.
[74]
Service de neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, Lyon, France.;Centre des Neurosciences de Lyon, Observatoire Français de la Sclérose en Plaques, INSERM 1028 et CNRS UMR5292, 69003, Lyon, France.;Université Claude Bernard Lyon 1, Faculté de médecine Lyon Est, F-69000, Lyon, France.
[75]
Department of Neurology, The Alfred Hospital, Melbourne, Australia.;Central Clinical School, Monash University, Melbourne, Australia.;Department of Neurology, Box Hill Hospital, Monash University, Melbourne, Australia.
[76]
CORe, Department of Medicine, University of Melbourne, L4 East, Grattan St, Melbourne, VIC, 3050, Australia. tomas.kalincik@unimelb.edu.au.;MS Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia. tomas.kalincik@unimelb.edu.au.
[77]
医学主题词
成年人(Adult);队列研究(Cohort Studies);女(雌)性(Female);随访研究(Follow-Up Studies);人类(Humans);免疫因子类(Immunologic Factors);免疫抑制剂(Immunosuppressive Agents);国际性(Internationality);纵向研究(Longitudinal Studies);男(雄)性(Male);中年人(Middle Aged);多发性硬化, 复发缓解性(Multiple Sclerosis, Relapsing-Remitting);登记(Registries);二级预防(Secondary Prevention)
DOI
10.1007/s40263-021-00860-7
PMID
34536228
发布时间
2022-02-16
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