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Monitoring the SARS-CoV-2 pandemic: screening algorithm with single nucleotide polymorphism detection for the rapid identification of established and emerging variants.

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第一作者： Joachim,Mertens

第一单位： Department of Microbiology and National Reference Centre for Respiratory Pathogens, University Hospital Antwerp, Edegem, Antwerp, Belgium; Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Wilrijk, Antwerp, Belgium.

作者： Joachim,Mertens ^[1] ; Jasmine,Coppens ^[2] ; Katherine,Loens ^[2] ; Marie,Le Mercier ^[3] ; Basil Britto,Xavier ^[4] ; Christine,Lammens ^[4] ; Sarah,Vandamme ^[3] ; Hilde,Jansens ^[2] ; Herman,Goossens ^[2] ; Veerle,Matheeussen ^[5]

作者单位： Department of Microbiology and National Reference Centre for Respiratory Pathogens, University Hospital Antwerp, Edegem, Antwerp, Belgium; Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Wilrijk, Antwerp, Belgium. ^[1] Department of Microbiology and National Reference Centre for Respiratory Pathogens, University Hospital Antwerp, Edegem, Antwerp, Belgium; Laboratory of Medical Biochemistry, University of Antwerp, Wilrijk, Antwerp, Belgium. ^[2] Department of Microbiology and National Reference Centre for Respiratory Pathogens, University Hospital Antwerp, Edegem, Antwerp, Belgium. ^[3] Laboratory of Medical Biochemistry, University of Antwerp, Wilrijk, Antwerp, Belgium. ^[4] Department of Microbiology and National Reference Centre for Respiratory Pathogens, University Hospital Antwerp, Edegem, Antwerp, Belgium; Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Wilrijk, Antwerp, Belgium; Laboratory of Medical Biochemistry, University of Antwerp, Wilrijk, Antwerp, Belgium. Electronic address: veerle.matheeussen@uza.be. ^[5]

关键词 Coronavirus disease 2019 Melting curve analysis Nucleic acid testing Polymerase chain reaction Severe acute respiratory syndrome coronavirus 2 Severe acute respiratory syndrome coronavirus 2 variants Testing algorithm Whole-genome sequencing

主题词算法(Algorithms);人类(Humans);突变(Mutation);疾病大流行(Pandemics);聚合酶链反应(Polymerase Chain Reaction);多态性, 单核苷酸(Polymorphism, Single Nucleotide)

DOI 10.1016/j.cmi.2021.09.007

PMID 34537361

发布时间 2023-11-07

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