Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer Patients.

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作者： Mingming,Li ^[1] ; Jiani,Chen ^[1] ; Shaoqun,Liu ^[2] ; Xiaomeng,Sun ^[3] ; Huilin,Xu ^[4] ; Qianmin,Gao ^[5] ; Xintao,Chen ^[5] ; Chaowen,Xi ^[3] ; Doudou,Huang ^[6] ; Yi,Deng ^[1] ; Feng,Zhang ^[1] ; Shouhong,Gao ^[1] ; Shi,Qiu ^[6] ; Xia,Tao ^[1] ; Jingwen,Zhai ^[1] ; Hua,Wei ^[1] ; Houshan,Yao ^[7] ; Wansheng,Chen ^[5]

作者单位： Department of Pharmacy, Second Affiliated Hospital of Naval Medical University, Shanghai, China. ^[1] Department of Gastric Intestinal Surgery, Minhang Hospital, Fudan University, Shanghai, China. ^[2] Research Institute, GloriousMed Clinical Laboratory Co., Ltd., Shanghai, China. ^[3] Institutes of Biomedical Sciences, Fudan University, Shanghai, China. ^[4] Department of General Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, China. ^[5] Traditional Chinese Medicine Resource and Technology Center, Shanghai University of Traditional Chinese Medicine, Shanghai, China. ^[6] Department of Pharmacy, 905th Hospital of PLA Navy, Naval Medical University, Shanghai, China. ^[7]

关键词 DNA methylation adverse effects chemotherapy hand-foot syndrome immune response multi-omics spermine susceptible factors

DOI 10.3389/fphar.2021.746910

PMID 34539419

发布时间 2021-09-21

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Frontiers in pharmacology

2021年12卷

746910页

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Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer Patients.

Frontiers in pharmacology

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Frontiers in pharmacology

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Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer Patients.

Frontiers in pharmacology

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Frontiers in pharmacology

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