USP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A<sub>165b</sub> alternative splicing via regulating SRSF1 and SRPK1.

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第一作者： Xiu-Wu,Pan

第一单位： Department of Urology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai, 200092, China.

作者： Xiu-Wu,Pan ^[1] ; Da,Xu ^[2] ; Wen-Jin,Chen ^[2] ; Jia-Xin,Chen ^[2] ; Wei-Jie,Chen ^[2] ; Jian-Qing,Ye ^[2] ; Si-Shun,Gan ^[2] ; Wang,Zhou ^[2] ; Xu,Song ^[3] ; Lei,Shi ^[4] ; Xin-Gang,Cui ^[5]

作者单位： Department of Urology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai, 200092, China. ^[1] Depanrtment of Urology, Third Affiliated Hospital of the Second Military Medical University, Shanghai, 201805, China. ^[2] Depanrtment of Urology, Third Affiliated Hospital of the Second Military Medical University, Shanghai, 201805, China. brilliant212@163.com. ^[3] Department of Urology, Shanghai Seventh People's Hospital, Shandong, 200137, China. 1418855811@qq.com. ^[4] Department of Urology, Yantai Yuhuangding Hospital of Qingdao University Medical College, Shandong, 264000, China. shileiyhd@sina.com. ^[5] Department of Urology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai, 200092, China. cuixingang@smmu.edu.cn. ^[6]

关键词 Renal cell carcinoma SRPK1 SRSF1 USP39 VEGF-A alternative splicing

DOI 10.1186/s12935-021-02161-x

PMID 34544400

发布时间 2021-09-24

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