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Novel naphthyl based 1,2,4-trioxanes: Synthesis and in vivo efficacy in the Plasmodium yoelii nigeriensis in Swiss mice.

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第一作者： Manvika,Karnatak

第一单位： Department of Chemistry, Banasthali University, Banasthali Newai 304022, Rajasthan, India.

作者： Manvika,Karnatak ^[1] ; Mohammad,Hassam ^[2] ; Murugesan,Vanangamudi ^[3] ; Siddharth,Sharma ^[4] ; Dinesh,Kumar Yadav ^[4] ; Chandan,Singh ^[2] ; Sunil K,Puri ^[5] ; Varun,Rawat ^[6] ; Ved,Prakash Verma ^[7]

作者单位： Department of Chemistry, Banasthali University, Banasthali Newai 304022, Rajasthan, India. ^[1] Medicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10 Jankipuram Extension Sitapur Road, Lucknow 226031, India. ^[2] Amity Institute of Pharmacy, Amity University Madhya Pradesh, Gwalior 474005, India. ^[3] Department of Chemistry, Mohanlal Sukhadia University, Udaipur 313001, India. ^[4] Parasitology Division, CSIR-Central Drug Research Institute, Sector 10 Jankipuram Extension Sitapur Road, Lucknow 226031, India. ^[5] Amity School of Applied Sciences, Amity University Haryana, Gurugram 122413, India. ^[6] Medicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10 Jankipuram Extension Sitapur Road, Lucknow 226031, India; Department of Chemistry, Banasthali University, Banasthali Newai 304022, Rajasthan, India. Electronic address: vedprakash079@gmail.com. ^[7]

关键词 1,2,4-Trioxane Antimalarial Activity Endoperoxide Multidrug-Resistant Photooxygenation β-Hydroxyhydroperoxide