Engineering a 3D human intracranial aneurysm model using liquid-assisted injection molding and tuned hydrogels.

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作者： Kar Wey,Yong ^[1] ; Mohsen,Janmaleki ^[2] ; Mohammad,Pachenari ^[3] ; Alim P,Mitha ^[4] ; Amir,Sanati-Nezhad ^[5] ; Arindom,Sen ^[6]

作者单位： Department of Chemical and Petroleum Engineering, Pharmaceutical Production Research Facility, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; BioMEMS and Bioinspired Microfluidic Laboratory, Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Center of Bioengineering Research and Education, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada. ^[1] BioMEMS and Bioinspired Microfluidic Laboratory, Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Center of Bioengineering Research and Education, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB T2N 1N4, Canada. ^[2] Mechanical and Industrial Engineering Department, University of Illinois at Chicago, Chicago, IL, United States. ^[3] Department of Clinical Neurosciences, Foothills Medical Center, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada. ^[4] BioMEMS and Bioinspired Microfluidic Laboratory, Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Center of Bioengineering Research and Education, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada. Electronic address: amir.sanatinezhad@ucalgary.ca. ^[5] Department of Chemical and Petroleum Engineering, Pharmaceutical Production Research Facility, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Center of Bioengineering Research and Education, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada. Electronic address: asen@ucalgary.ca. ^[6]

关键词 Balloon catheter Biomaterial Biomimetic tissue In vitro hydrogel model Intracranial aneurysm Modified liquid-assisted injection molding

主题词明胶(Gelatin);人类(Humans);水凝胶类(Hydrogels);颅内动脉瘤(Intracranial Aneurysm);甲基丙烯酸盐(Methacrylates);组织工程(Tissue Engineering)

DOI 10.1016/j.actbio.2021.09.022

PMID 34547516

发布时间 2021-12-14

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准确一般字义偏差语意偏离译文作用小提交