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NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE.

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第一作者： Spiros,Georgakis

第一单位： Laboratory of Rheumatology, Autoimmunity and Inflammation, University of Crete, Medical School, Iraklio, Greece.;Infections and Immunity, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Iraklio, Greece.

作者： Spiros,Georgakis ^[1] ; Katerina,Gkirtzimanaki ^[1] ; Garyfalia,Papadaki ^[1] ; Hariklia,Gakiopoulou ^[2] ; Elias,Drakos ^[3] ; Maija-Leena,Eloranta ^[4] ; Manousos,Makridakis ^[5] ; Georgia,Kontostathi ^[5] ; Jerome,Zoidakis ^[5] ; Eirini,Baira ^[6] ; Lars,Rönnblom ^[4] ; Dimitrios T,Boumpas ^[7] ; Prodromos,Sidiropoulos ^[1] ; Panayotis,Verginis ^[8] ; George,Bertsias ^[1]

作者单位： Laboratory of Rheumatology, Autoimmunity and Inflammation, University of Crete, Medical School, Iraklio, Greece.;Infections and Immunity, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Iraklio, Greece. ^[1] 1st Department of Pathology, National and Kapodistrian University of Athens Medical School, Athens, Greece. ^[2] Department of Pathology, University of Crete, Medical School, Iraklio, Greece. ^[3] Department of Medical Sciences, Rheumatology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden. ^[4] Biotechnology Division, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. ^[5] Laboratory of Toxicological Assessment of Pesticides, Scientific Directorate of Pesticides Assessment and Phytopharmacy, Benaki Phytopathological Institute, Athens, Greece. ^[6] Center of Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece.;Joint Rheumatology Program and 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece. ^[7] Infections and Immunity, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Iraklio, Greece.;Laboratory of Immune Regulation and Tolerance, University of Crete, Medical School, Iraklio, Greece. ^[8]

关键词 Autoimmunity Cytokines Inflammation Lupus Neutrophils

医学主题词病例对照研究(Case-Control Studies);树突细胞(Dendritic Cells);人类(Humans);干扰素α(Interferon-alpha);红斑狼疮, 系统性(Lupus Erythematosus, Systemic)

DOI 10.1172/jci.insight.147671

PMID 34554930

发布时间 2025-05-30

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准确一般字义偏差语意偏离译文作用小提交