Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial.

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作者： Carolyn Y,Ho ^[1] ; Sharlene M,Day ^[2] ; Anna,Axelsson ^[3] ; Mark W,Russell ^[4] ; Kenneth,Zahka ^[2] ; Harry M,Lever ^[5] ; Alexandre C,Pereira ^[5] ; Steven D,Colan ^[6] ; Renee,Margossian ^[7] ; Anne M,Murphy ^[7] ; Charles,Canter ^[8] ; Richard G,Bach ^[9] ; Matthew T,Wheeler ^[9] ; Joseph W,Rossano ^[10] ; Anjali T,Owens ^[11] ; Henning,Bundgaard ^[3] ; Lee,Benson ^[4] ; Luisa,Mestroni ^[12] ; Matthew R G,Taylor ^[13] ; Amit R,Patel ^[14] ; Ivan,Wilmot ^[14] ; Philip,Thrush ^[15] ; Jose D,Vargas ^[16] ; Jonathan H,Soslow ^[17] ; Jason R,Becker ^[18] ; Christine E,Seidman ^[19] ; Neal K,Lakdawala ^[19] ; Allison L,Cirino ^[20] ; VANISH Investigators ^[21] ; Kristin M,Burns ^[22] ; John J V,McMurray ^[21] ; Calum A,MacRae ^[21] ; Scott D,Solomon ^[23] ; E John,Orav ^[24] ; Eugene,Braunwald ^[21]

作者单位： Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. cho@bwh.harvard.edu. ^[1] University of Michigan, Ann Arbor, MI, USA. ^[2] Division of Cardiovascular Medicine Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. ^[3] Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. ^[4] Cleveland Clinic Foundation, Cleveland, OH, USA. ^[5] Laboratory of Genetics and Molecular Cardiology, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil. ^[6] Department of Cardiology, Boston Children's Hospital, Boston, MA, USA. ^[7] Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. ^[8] Washington University School of Medicine, St. Louis, MO, USA. ^[9] Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. ^[10] Children's Hospital of Philadelphia, Philadelphia, PA, USA. ^[11] Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. ^[12] Toronto Hospital for Sick Children, Toronto, ON, Canada. ^[13] University of Colorado Anschutz Medical Campus, Aurora, CO, USA. ^[14] Departments of Medicine and Radiology, University of Chicago, Chicago, IL, USA. ^[15] Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. ^[16] Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA. ^[17] MedStar Heart and Vascular Institute, Washington, USA. ^[18] Vanderbilt University Medical Center, Nashville, TN, USA. ^[19] Division of Cardiology, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, PA, USA. ^[20] Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[21] Howard Hughes Medical Institute, Chevy Chase, MD, USA. ^[22] Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. ^[23] British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, UK. ^[24]