Discovery of Selective Inhibitors for <i>In Vitro</i> and <i>In Vivo</i> Interrogation of Skeletal Myosin II.

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作者： Laszlo,Radnai ^[1] ; Matthew,Surman ^[2] ; Madalyn,Hafenbreidel ^[3] ; Erica J,Young ^[1] ; Rebecca F,Stremel ^[2] ; Li,Lin ^[1] ; Bilel,Bdiri ^[2] ; Paolo,Pasetto ^[1] ; Xiaomin,Jin ^[2] ; Mackenzie,Geedy ^[1] ; Joni-Rae,Partridge ^[1] ; Aagam,Patel ^[3] ; Michael,Conlon ^[3] ; James R,Sellers ^[3] ; Michael D,Cameron ^[3] ; Gavin,Rumbaugh ^[3] ; Patrick R,Griffin ^[3] ; Theodore M,Kamenecka ^[4] ; Courtney A,Miller ^[1]

作者单位： Department of Molecular Medicine, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States. ^[1] Department of Neuroscience, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States. ^[2] Albany Molecular Research Inc., 26 Corporate Circle, Albany, New York 12212, United States. ^[3] Laboratory of Molecular Physiology, NHLBI, National Institutes of Health, 50 South Drive, B50/3529, Bethesda, Maryland 20892-8015, United States. ^[4]

主题词动物(Animals);小鼠(Mice);分子结构(Molecular Structure);肌, 骨骼(Muscle, Skeletal);肌球蛋白Ⅱ型(Myosin Type II)

DOI 10.1021/acschembio.1c00067

PMID 34558887

发布时间 2023-04-15

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