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TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.

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第一作者： Jeffrey M,Collins

第一单位： Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.

作者： Jeffrey M,Collins ^[1] ; Dean P,Jones ^[1] ; Ashish,Sharma ^[2] ; Manoj,Khadka ^[3] ; Ken H,Liu ^[1] ; Russell R,Kempker ^[1] ; Brendan,Prideaux ^[4] ; Kristal,Maner-Smith ^[3] ; Nestani,Tukvadze ^[5] ; N Sarita,Shah ^[6] ; James C M,Brust ^[7] ; Rafick-Pierre,Sékaly ^[2] ; Neel R,Gandhi ^[6] ; Henry M,Blumberg ^[6] ; Eric A,Ortlund ^[3] ; Thomas R,Ziegler ^[8]

作者单位： Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America. ^[1] Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, United States of America. ^[2] Department of Biochemistry, Emory University, Atlanta, Georgia, United States of America. ^[3] Department of Neuroscience, Cell Biology, & Anatomy, University of Texas Medical Branch, Galveston, Texas, United States of America. ^[4] National Center for Tuberculosis and Lung Diseases, Tbilisi, Georgia. ^[5] Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.;Department of Global Health, Emory University Rollins School of Public Health, Atlanta, Georgia, United States of America.;Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, United States of America. ^[6] Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America. ^[7] Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.;Section of Endocrinology, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America. ^[8]

医学主题词柠檬酸循环(Citric Acid Cycle);人类(Humans);炎症(Inflammation);信号传导(Signal Transduction);结核, 肺(Tuberculosis, Pulmonary)

DOI 10.1371/journal.ppat.1009941

PMID 34559866

发布时间 2022-12-02

基金项目