DNA interaction, anticancer, cytotoxicity and genotoxicity studies with potential pyrazine-bipyrazole dinuclear µ-oxo bridged Au(III) complexes.

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作者： Darshana N,Kanthecha ^[1] ; Bhupesh S,Bhatt ^[2] ; Mohan N,Patel ^[1] ; Foram U,Vaidya ^[3] ; Chandramani,Pathak ^[4]

作者单位： Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar, Anand, Gujarat, 388 120, India. ^[1] Department of Applied and Interdisciplinary Sciences, IICISST, Sardar Patel University, Vallabh Vidyanagar, Anand, Gujarat, 388 120, India. ^[2] Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar, Anand, Gujarat, 388 120, India. jeenen@gmail.com. ^[3] Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Koba Institutional Area, Gandhinagar, Gujarat, 382007, India. ^[4] Amity Institute of Biotechnology, Amity University, Manesar, Gurgaon, Haryana, 122413, India. ^[5]

关键词 Cell viability DNA Dinuclear Au(III) complex Genotoxicity MTT assay

主题词抗肿瘤药(Antineoplastic Agents);配位络合物(Coordination Complexes);DNA(DNA);吡嗪类(Pyrazines);谱学, 傅里叶变换红外(Spectroscopy, Fourier Transform Infrared)

DOI 10.1007/s11030-021-10317-0

PMID 34561737

发布时间 2022-08-02

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