Novel Ferrocene Derivatives Induce Apoptosis through Mitochondria-Dependent and Cell Cycle Arrest via PI3K/Akt/mTOR Signaling Pathway in T Cell Acute Lymphoblastic Leukemia.

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第一作者： Liao,Zeng

第一单位： Engineering Research Centre of Molecular Medicine of Ministry of Education, Fujian Key Laboratory of Molecular Medicine, Key Laboratory of Precision Medicine and Molecular Diagnosis of Fujian Universities, Xiamen Key Laboratory of Marine and Gene Drugs, School of Medicine, Huaqiao University, Xiamen 361021, China.

作者： Liao,Zeng ^[1] ; Mingqing,Tang ^[1] ; Chao,Pi ^[2] ; Jianrong,Zheng ^[1] ; Sanxing,Gao ^[1] ; Titaua,Chabanne ^[1] ; Remi,Chauvin ^[3] ; Wenzhao,Cheng ^[1] ; Hongjun,Lin ^[3] ; Ruian,Xu ^[1] ; Xiuling,Cui ^[1]

作者单位： Engineering Research Centre of Molecular Medicine of Ministry of Education, Fujian Key Laboratory of Molecular Medicine, Key Laboratory of Precision Medicine and Molecular Diagnosis of Fujian Universities, Xiamen Key Laboratory of Marine and Gene Drugs, School of Medicine, Huaqiao University, Xiamen 361021, China. ^[1] Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, Green Catalysis Center, and College of Chemistry, Zhengzhou University, Zhengzhou 450052, China. ^[2] LCC-CNRS, Université de Toulouse, UPS, 205 Route de Narbonne, 31077 Toulouse, France. ^[3]

关键词 PI3K/Akt/mTOR signaling pathway T cell acute lymphoblastic leukemia apoptosis cell cycle ferrocene derivatives mitochondrial membrane potential reactive oxygen species

DOI 10.3390/cancers13184677

PMID 34572904

发布时间 2021-10-01

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