Artificial Neural Networks to Predict the Apparent Degree of Supersaturation in Supersaturated Lipid-Based Formulations: A Pilot Study.

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作者： Harriet,Bennett-Lenane ^[1] ; Joseph P,O'Shea ^[1] ; Jack D,Murray ^[1] ; Alexandra-Roxana,Ilie ^[1] ; René,Holm ^[2] ; Martin,Kuentz ^[2] ; Brendan T,Griffin ^[3]

作者单位： School of Pharmacy, University College Cork, T12 YT20 Cork, Ireland. ^[1] Drug Product Development, Janssen Research and Development, Johnson & Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium. ^[2] Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, DK-5230 Odense, Denmark. ^[3] School of Life Sciences, University of Applied Sciences and Arts Northwestern Switzerland, Hofackerstrasse 30, 4132 Muttenz, Switzerland. ^[4]

关键词 computational pharmaceutics lipid-based drug delivery machine learning supersaturated lipid-based formulations

DOI 10.3390/pharmaceutics13091398

PMID 34575483

发布时间 2021-10-01

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