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首页> Nature communications> An immune response characterizes early Alzheimer's disease pathology and subjective cognitive impairment in hydrocephalus biopsies.

An immune response characterizes early Alzheimer's disease pathology and subjective cognitive impairment in hydrocephalus biopsies.

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作者： Wenrui,Huang ^[1] ; Anne Marie,Bartosch ^[2] ; Harrison,Xiao ^[1] ; Suvrajit,Maji ^[2] ; Elliot H H,Youth ^[1] ; Xena,Flowers ^[2] ; Sandra,Leskinen ^[1] ; Zeljko,Tomljanovic ^[2] ; Gail,Iodice ^[2] ; Deborah,Boyett ^[2] ; Eleonora,Spinazzi ^[2] ; Vilas,Menon ^[3] ; Robert A,McGovern ^[2] ; Guy M,McKhann ^[4] ; Andrew F,Teich ^[4]

作者单位： Department of Pathology and Cell Biology, Columbia University, New York, NY, USA. ^[1] Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. ^[2] Department of Neurology, Columbia University, New York, NY, USA. ^[3] Department of Neurosurgery, Columbia University, New York, NY, USA. ^[4] Department of Neurosurgery, University of Minnesota, Minneapolis, MN, USA. ^[5] Department of Pathology and Cell Biology, Columbia University, New York, NY, USA. aft25@cumc.columbia.edu. ^[6] Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. aft25@cumc.columbia.edu. ^[7] Department of Neurology, Columbia University, New York, NY, USA. aft25@cumc.columbia.edu. ^[8]

主题词发病年龄(Age of Onset);老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);星形细胞(Astrocytes);活组织检查(Biopsy);大脑皮质(Cerebral Cortex);女(雌)性(Female);基因调控网络(Gene Regulatory Networks);人类(Humans);脑积水, 正常压力(Hydrocephalus, Normal Pressure);男(雄)性(Male);小神经胶质细胞(Microglia);神经心理学测验(Neuropsychological Tests);回顾性研究(Retrospective Studies)

DOI 10.1038/s41467-021-25902-y

PMID 34580300

发布时间 2024-05-07

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Nature communications

Nature communications

2021年12卷1期

5659页

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