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Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study.

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第一作者: Annika,Fendler
第一单位: Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Equal contribution.
作者: Annika,Fendler [1] ; Lewis,Au [2] ; Scott T C,Shepherd [2] ; Fiona,Byrne [3] ; Maddalena,Cerrone [4] ; Laura Amanda,Boos [5] ; Karolina,Rzeniewicz [3] ; William,Gordon [3] ; Ben,Shum [6] ; Camille L,Gerard [3] ; Barry,Ward [3] ; Wenyi,Xie [3] ; Andreas M,Schmitt [5] ; Nalinie,Joharatnam-Hogan [5] ; Georgina H,Cornish [7] ; Martin,Pule [8] ; Leila,Mekkaoui [9] ; Kevin W,Ng [7] ; Eleanor,Carlyle [5] ; Kim,Edmonds [5] ; Lyra,Del Rosario [5] ; Sarah,Sarker [5] ; Karla,Lingard [5] ; Mary,Mangwende [5] ; Lucy,Holt [5] ; Hamid,Ahmod [5] ; Richard,Stone [9] ; Camila,Gomes [9] ; Helen R,Flynn [10] ; Ana,Agua-Doce [11] ; Philip,Hobson [11] ; Simon,Caidan [12] ; Michael,Howell [13] ; Mary,Wu [13] ; Robert,Goldstone [14] ; Margaret,Crawford [14] ; Laura,Cubitt [14] ; Harshil,Patel [15] ; Mike,Gavrielides [16] ; Emma,Nye [17] ; Ambrosius P,Snijders [10] ; James I,MacRae [18] ; Jerome,Nicod [14] ; Firza,Gronthoud [19] ; Robyn L,Shea [20] ; Christina,Messiou [21] ; David,Cunningham [22] ; Ian,Chau [22] ; Naureen,Starling [22] ; Nicholas,Turner [23] ; Liam,Welsh [24] ; Nicholas,van As [25] ; Robin L,Jones [26] ; Joanne,Droney [27] ; Susana,Banerjee [28] ; Kate C,Tatham [29] ; Shaman,Jhanji [29] ; Mary,O'Brien [30] ; Olivia,Curtis [30] ; Kevin,Harrington [31] ; Shreerang,Bhide [32] ; Jessica,Bazin [33] ; Anna,Robinson [33] ; Clemency,Stephenson [33] ; Tim,Slattery [5] ; Yasir,Khan [5] ; Zayd,Tippu [5] ; Isla,Leslie [5] ; Spyridon,Gennatas [34] ; Alicia,Okines [35] ; Alison,Reid [36] ; Kate,Young [5] ; Andrew J S,Furness [5] ; Lisa,Pickering [5] ; Sonia,Gandhi [37] ; Steve,Gamblin [38] ; Charles,Swanton [39] ; Emma,Nicholson [33] ; Sacheen,Kumar [22] ; Nadia,Yousaf [40] ; Katalin A,Wilkinson [41] ; Anthony,Swerdlow [42] ; Ruth,Harvey [43] ; George,Kassiotis [7] ; James,Larkin [5] ; Robert J,Wilkinson [44] ; Samra,Turajlic [6]
作者单位: Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Equal contribution. [1] Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.;Equal contribution. [2] Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. [3] Tuberculosis Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Department of Infectious Disease, Imperial College London, W12 0NN, UK. [4] Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [5] Cancer Dynamics Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [6] Retroviral Immunology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. [7] Research Department of Haematology at University College London Cancer Institute, WC1E 6DD, London, UK.;Autolus Limited, The MediaWorks, 191 Wood Lane, London, W12 7F. [8] Autolus Limited, The MediaWorks, 191 Wood Lane, London, W12 7F. [9] Mass Spectrometry Proteomics Science Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK. [10] Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK. [11] Safety, Health & Sustainability, The Francis Crick Institute, London, NW1 1AT, UK. [12] High Throughput Screening Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. [13] Advanced Sequencing Facility, The Francis Crick Institute, London, NW1 1AT, UK. [14] Department of Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK. [15] Scientific Computing Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK. [16] Experimental Histopathology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. [17] Metabolomics Scientific Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK. [18] Department of Pathology, The Royal Marsden NHS Foundation Trust, London, NW1 1AT, UK. [19] Department of Pathology, The Royal Marsden NHS Foundation Trust, London, NW1 1AT, UK.;Translational Cancer Biochemistry Laboratory, The Institute of Cancer Research, London, SW7 3RP, UK. [20] Department of Radiology, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [21] Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey SM2 5PT. [22] Breast Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [23] Neuro-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [24] Clinical Oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [25] Sarcoma Unit, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, SW3 6JJ, UK. [26] Palliative Medicine, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [27] Gynaecology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [28] Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [29] Lung Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [30] Head and Neck, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.;Targeted Therapy Team, The Institute of Cancer Research, London, SW7 3RP, UK. [31] Head and Neck, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [32] Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [33] Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.;Department of Medical Oncology, 14th Floor, Great Maze Pond Road, Tower Wing, Guy's Hospital, London SE1 9RY, UK. [34] Breast Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.;Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [35] Uro-oncology unit, The Royal Marsden NHS Foundation Trust, Surrey, SM2 5PT. [36] Neurodegeneration Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG. [37] Structural Biology of Disease Processes Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. [38] Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;University College London Cancer Institute, London WC1E 6DD, UK. [39] Lung Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.;Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK. [40] Tuberculosis Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Wellcome Center for Infectious Disease Research in Africa, University Cape Town, Observatory 7925, Republic of South Africa. [41] Division of Genetics and Epidemiology and Division of Breast Cancer Research, The Institute of Cancer Research, London, SW7 3RP, UK. [42] Worldwide Influenza Centre, The Francis Crick Institute, London, NW1 1AT, UK. [43] Tuberculosis Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;Department of Infectious Disease, Imperial College London, W12 0NN, UK.;Wellcome Center for Infectious Disease Research in Africa, University Cape Town, Observatory 7925, Republic of South Africa. [44]
DOI 10.21203/rs.3.rs-916427/v1
PMID 34580668
发布时间 2025-05-30
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