换一批Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
第一作者：
Anna V,Mikhaylova
第一单位：
Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
作者：
Anna V,Mikhaylova [1]
;
Caitlin P,McHugh [1]
;
Linda M,Polfus [2]
;
Laura M,Raffield [3]
;
Meher Preethi,Boorgula [4]
;
Thomas W,Blackwell [5]
;
Jennifer A,Brody [6]
;
Jai,Broome [1]
;
Nathalie,Chami [7]
;
Ming-Huei,Chen [8]
;
Matthew P,Conomos [1]
;
Corey,Cox [4]
;
Joanne E,Curran [9]
;
Michelle,Daya [4]
;
Lynette,Ekunwe [10]
;
David C,Glahn [11]
;
Nancy,Heard-Costa [12]
;
Heather M,Highland [13]
;
Brian D,Hobbs [14]
;
Yann,Ilboudo [15]
;
Deepti,Jain [1]
;
Leslie A,Lange [4]
;
Tyne W,Miller-Fleming [16]
;
Nancy,Min [10]
;
Jee-Young,Moon [17]
;
Michael H,Preuss [7]
;
Jonathon,Rosen [18]
;
Kathleen,Ryan [19]
;
Albert V,Smith [5]
;
Quan,Sun [18]
;
Praveen,Surendran [20]
;
Paul S,de Vries [21]
;
Klaudia,Walter [22]
;
Zhe,Wang [7]
;
Marsha,Wheeler [23]
;
Lisa R,Yanek [24]
;
Xue,Zhong [16]
;
Goncalo R,Abecasis [5]
;
Laura,Almasy [25]
;
Kathleen C,Barnes [4]
;
Terri H,Beaty [26]
;
Lewis C,Becker [27]
;
John,Blangero [9]
;
Eric,Boerwinkle [21]
;
Adam S,Butterworth [28]
;
Sameer,Chavan [4]
;
Michael H,Cho [29]
;
Hélène,Choquet [30]
;
Adolfo,Correa [10]
;
Nancy,Cox [16]
;
Dawn L,DeMeo [14]
;
Nauder,Faraday [31]
;
Myriam,Fornage [32]
;
Robert E,Gerszten [33]
;
Lifang,Hou [34]
;
Andrew D,Johnson [8]
;
Eric,Jorgenson [35]
;
Robert,Kaplan [17]
;
Charles,Kooperberg [36]
;
Kousik,Kundu [37]
;
Cecelia A,Laurie [1]
;
Guillaume,Lettre [15]
;
Joshua P,Lewis [19]
;
Bingshan,Li [38]
;
Yun,Li [39]
;
Donald M,Lloyd-Jones [40]
;
Ruth J F,Loos [7]
;
Ani,Manichaikul [41]
;
Deborah A,Meyers [42]
;
Braxton D,Mitchell [43]
;
Alanna C,Morrison [21]
;
Debby,Ngo [44]
;
Deborah A,Nickerson [23]
;
Suraj,Nongmaithem [22]
;
Kari E,North [13]
;
Jeffrey R,O'Connell [19]
;
Victor E,Ortega [45]
;
Nathan,Pankratz [46]
;
James A,Perry [47]
;
Bruce M,Psaty [48]
;
Stephen S,Rich [41]
;
Nicole,Soranzo [49]
;
Jerome I,Rotter [50]
;
Edwin K,Silverman [14]
;
Nicholas L,Smith [51]
;
Hua,Tang [52]
;
Russell P,Tracy [53]
;
Timothy A,Thornton [54]
;
Ramachandran S,Vasan [55]
;
Joe,Zein [56]
;
Rasika A,Mathias [57]
;
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium [58]
;
Alexander P,Reiner [59]
;
Paul L,Auer
作者单位：
Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
[1]
Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
[2]
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
[3]
Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
[4]
TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
[5]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98105, USA.
[6]
The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.
[7]
Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA.
[8]
Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA.
[9]
Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
[10]
Department of Psychiatry, Boston Children's Hospital and Harvard Medical School, Boston, MA 02155, USA.
[11]
National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA.
[12]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
[13]
Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
[14]
Montréal Heart Institute, Montréal, Québec H1T 1C8, Canada; Faculté de Médecine, Université de Montréal, Montréal, Québec H1T 1C8, Canada.
[15]
Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA.
[16]
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
[17]
Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
[18]
Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
[19]
British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge CB1 8RN, UK; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
[20]
Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
[21]
Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
[22]
Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA.
[23]
Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
[24]
Department of Biomedical and Health Informatics, the Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
[25]
School of Public Health, John Hopkins University, Baltimore, MD 21205, USA.
[26]
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
[27]
British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge CB1 8RN, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge CB1 8RN, UK; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge CB1 8RN, UK.
[28]
Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
[29]
Division of Research, Kaiser Permanente Northern California, Oakland, CA 94601, USA.
[30]
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
[31]
University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
[32]
Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
[33]
Institute for Public Health and Medicine, Northwestern University, Chicago, IL 60661, USA.
[34]
Regeneron Genetics Center, Tarrytown, NY 10591, USA.
[35]
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
[36]
Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; Department of Haematology, University of Cambridge, Cambridge CB1 8RN, UK.
[37]
Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.
[38]
Departments of Biostatistics, Genetics, and Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
[39]
Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60661, USA; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60661, USA.
[40]
Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
[41]
Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ 85724, USA.
[42]
Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD 21201, USA.
[43]
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
[44]
Department of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.
[45]
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
[46]
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
[47]
Department of Epidemiology, University of Washington, Seattle, WA 98105, USA; Department of Health Service, University of Washington, Seattle, WA 98105, USA; Department of Medicine, University of Washington, Seattle, WA 98105, USA.
[48]
Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge CB1 8RN, UK; Department of Haematology, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge CB1 8RN, UK.
[49]
The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA.
[50]
Department of Epidemiology, University of Washington, Seattle, WA 98105, USA; Department of Health Service, University of Washington, Seattle, WA 98105, USA; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA 98105, USA.
[51]
Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
[52]
Department of Pathology and Laboratory Medicine and Department of Biochemistry, University of Vermont Larner College of Medicine, Colchester, VT 05446, USA.
[53]
Department of Biostatistics, University of Washington, Seattle, WA 98105, USA; Regeneron Genetics Center, Tarrytown, NY 10591, USA.
[54]
National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Departments of Cardiology and Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
[55]
Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
[56]
Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
[57]
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: apreiner@uw.edu.
[58]
Zilber School of Public Health, University of Wisconsin, Milwaukee, Milwaukee, WI 53205, USA. Electronic address: pauer@mcw.edu.
[59]
医学主题词
哮喘(Asthma);皮炎, 特应性(Dermatitis, Atopic);疾病遗传易感性(Genetic Predisposition to Disease);基因组, 人(Genome, Human);全基因组关联研究(Genome-Wide Association Study);人类(Humans);白细胞(Leukocytes);国立心肺血液研究所(美国)(National Heart, Lung, and Blood Institute (U.S.));表型(Phenotype);多态性, 单核苷酸(Polymorphism, Single Nucleotide);预后(Prognosis);蛋白质组(Proteome);肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive);数量性状基因座位(Quantitative Trait Loci);美国(United States)
DOI
10.1016/j.ajhg.2021.08.007
PMID
34582791
发布时间
2023-02-17
- 浏览2
American journal of human genetics
American journal of human genetics
1836-1851页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
