Apolipoprotein Mimetic Peptide Inhibits Neutrophil-Driven Inflammatory Damage via Membrane Remodeling and Suppression of Cell Lysis.

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第一作者： Michelle W,Lee

第一单位： Department of Bioengineering, University of California, Los Angeles, California 90095, United States.

作者： Michelle W,Lee ^[1] ; Elizabeth Wei-Chia,Luo ^[1] ; Carlos,Silvestre-Roig ^[2] ; Yashes,Srinivasan ^[3] ; Kiyotaka,Akabori ^[1] ; Patricia,Lemnitzer ^[4] ; Nathan W,Schmidt ^[2] ; Ghee Hwee,Lai ^[1] ; Christian D,Santangelo ^[5] ; Oliver,Soehnlein ^[1] ; Gerard C L,Wong ^[6]

作者单位： Department of Bioengineering, University of California, Los Angeles, California 90095, United States. ^[1] Institute of Experimental Pathology, Center for Molecular Biology of Inflammation (ZMBE), University of Münster, 48149 Münster, Germany. ^[2] Institute for Cardiovascular Prevention (IPEK), LMU Munich, 80336 Munich, Germany. ^[3] Department of Physics, University of Massachusetts, Amherst, Massachusetts 01003, United States. ^[4] Ginkgo Bioworks, 27 Drydock Avenue, Boston, Massachusetts 02210, United States. ^[5] Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, 60 Nanyang Drive, SBS-01N-27, Singapore 637551. ^[6] Department of Physics, Syracuse University, Syracuse, New York 13244, United States. ^[7] Department of Physiology and Pharmacology (FyFa), Karolinska Institute, 171 77 Stockholm, Sweden. ^[8]

关键词 apolipoprotein cell death chronic inflammation membrane remodeling neutrophils peptide?membrane interactions

主题词细胞死亡(Cell Death);组蛋白类(Histones);中性白细胞(Neutrophils);肽类(Peptides)

DOI 10.1021/acsnano.1c03978

PMID 34586780

发布时间 2022-01-05

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