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Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.

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第一作者: Kendelle J,Murphy
第一单位: Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
作者单位: Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia. [1] Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Oncode Institute, Division of Molecular Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands. [2] Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520 Turku, Finland. [3] Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia. [4] Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.;NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, NSW 2065, Australia.;Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, NSW 2064, Australia. [5] Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.;West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK. [6] Department of Surgery, Royal North Shore Hospital, Sydney, NSW 2065, Australia. [7] University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia. [8] Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.;NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, NSW 2065, Australia.;Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, NSW 2064, Australia.;Department of Anatomical Pathology, SydPath, Darlinghurst, NSW 2010, Australia. [9] INSERM UMR, Tumour Biomechanics, Strasbourg, France.;Université de Strasbourg, Strasbourg, France.;Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France. [10] Centre for Cancer Biology, SA Pathology and University of South Australia, SA, Australia.;Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia. [11] Dermatology, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.;Cancer Services, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.;Centenary Institute, The University of Sydney, Camperdown, NSW, Australia. [12] ANZAC Research Institute, Sydney, NSW 2139, Australia.;Faculty of Medicine and Health, Concord Clinical School, University of Sydney, Sydney, NSW 2000, Australia. [13] Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.;Medical Oncology, Chris O'Brien Lifehouse, Camperdown, NSW 2006, Australia. [14] Cancer Program and Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia. [15] James Watt School of Engineering, University of Glasgow, Glasgow, UK. [16] Department of Bioengineering and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA, USA. [17] Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.;Cancer Research UK Beatson Institute, Glasgow, UK. [18]
DOI 10.1126/sciadv.abh0363
PMID 34586840
发布时间 2026-03-07
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2021年7卷40期

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