Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.
第一作者:
Kendelle J,Murphy
第一单位:
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
作者:
Kendelle J,Murphy [1]
;
Daniel A,Reed [1]
;
Claire,Vennin [2]
;
James R W,Conway [3]
;
Max,Nobis [1]
;
Julia X,Yin [1]
;
Cecilia R,Chambers [1]
;
Brooke A,Pereira [1]
;
Victoria,Lee [4]
;
Elysse C,Filipe [1]
;
Michael,Trpceski [4]
;
Shona,Ritchie [1]
;
Morghan C,Lucas [1]
;
Sean C,Warren [1]
;
Joanna N,Skhinas [4]
;
Astrid,Magenau [1]
;
Xanthe L,Metcalf [4]
;
Janett,Stoehr [4]
;
Gretel,Major [4]
;
Ashleigh,Parkin [1]
;
Romain,Bidanel [4]
;
Ruth J,Lyons [4]
;
Anaiis,Zaratzian [4]
;
Michael,Tayao [4]
;
Andrew,Da Silva [4]
;
Lea,Abdulkhalek [4]
;
Australian Pancreatic Genome Initiative (APGI) [5]
;
Australian Pancreatic Cancer Matrix Atlas (APMA) [4]
;
Anthony J,Gill [6]
;
Amber L,Johns [7]
;
Andrew V,Biankin [8]
;
Jaswinder,Samra [9]
;
Sean M,Grimmond [10]
;
Angela,Chou [11]
;
Jacky G,Goetz [12]
;
Michael S,Samuel [13]
;
J Guy,Lyons [1]
;
Andrew,Burgess [14]
;
C Elizabeth,Caldon [15]
;
Lisa G,Horvath [16]
;
Roger J,Daly [17]
;
Nikolaj,Gadegaard [18]
;
Yingxiao,Wang [18]
;
Owen J,Sansom [1]
;
Jennifer P,Morton [1]
;
Thomas R,Cox [1]
;
Marina,Pajic [1]
;
David,Herrmann ;
Paul,Timpson
作者单位:
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
[1]
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Oncode Institute, Division of Molecular Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands.
[2]
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520 Turku, Finland.
[3]
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.
[4]
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.;NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, NSW 2065, Australia.;Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, NSW 2064, Australia.
[5]
Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.;West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK.
[6]
Department of Surgery, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
[7]
University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia.
[8]
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.;NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, NSW 2065, Australia.;Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, NSW 2064, Australia.;Department of Anatomical Pathology, SydPath, Darlinghurst, NSW 2010, Australia.
[9]
INSERM UMR, Tumour Biomechanics, Strasbourg, France.;Université de Strasbourg, Strasbourg, France.;Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France.
[10]
Centre for Cancer Biology, SA Pathology and University of South Australia, SA, Australia.;Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.
[11]
Dermatology, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.;Cancer Services, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.;Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.
[12]
ANZAC Research Institute, Sydney, NSW 2139, Australia.;Faculty of Medicine and Health, Concord Clinical School, University of Sydney, Sydney, NSW 2000, Australia.
[13]
Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia.;St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.;Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.;Medical Oncology, Chris O'Brien Lifehouse, Camperdown, NSW 2006, Australia.
[14]
Cancer Program and Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.
[15]
James Watt School of Engineering, University of Glasgow, Glasgow, UK.
[16]
Department of Bioengineering and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA, USA.
[17]
Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.;Cancer Research UK Beatson Institute, Glasgow, UK.
[18]
DOI
10.1126/sciadv.abh0363
PMID
34586840
发布时间
2026-03-07
- 浏览2
Science advances
Science advances
2021年7卷40期
eabh0363页
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