Generation, characterization, and drug sensitivities of 12 patient-derived IDH1-mutant glioma cell cultures.

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第一作者： Cassandra,Verheul

第一单位： Department of Neurosurgery, Brain Tumor Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, The Netherlands.

作者： Cassandra,Verheul ^[1] ; Ioannis,Ntafoulis ^[1] ; Trisha V,Kers ^[1] ; Youri,Hoogstrate ^[2] ; Pier G,Mastroberardino ^[3] ; Sander,Barnhoorn ^[3] ; César,Payán-Gómez ^[4] ; Romain,Tching Chi Yen ^[5] ; Eduard A,Struys ^[6] ; Stijn L W,Koolen ^[7] ; Clemens M F,Dirven ^[8] ; Sieger,Leenstra ^[9] ; Pim J,French ^[1] ; Martine L M,Lamfers ^[1]

作者单位： Department of Neurosurgery, Brain Tumor Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, The Netherlands. ^[1] Department of Neurology, Brain Tumor Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, The Netherlands. ^[2] Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, Zuid-Holland, The Netherlands. ^[3] Department of Biology, Faculty of Natural Sciences, Universidad del Rosario, Bogotá,Colombia. ^[4] Information Technologies for Translational Medicine (ITTM), Esch-Sur-Alzette, Luxembourg. ^[5] Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Sur-Alzette,Luxembourg. ^[6] Metabolic Unit, Department of Clinical Chemistry, Amsterdam University Medical Center, Noord-Holland, The Netherlands. ^[7] Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Zuid-Holland, The Netherlands. ^[8] Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, Zuid-Holland, The Netherlands. ^[9]

关键词 IDH1 drug repurposing glioma patient-derived cell culture preclinical models

DOI 10.1093/noajnl/vdab103

PMID 34595478

发布时间 2022-04-27

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Neuro-oncology advances

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Generation, characterization, and drug sensitivities of 12 patient-derived IDH1-mutant glioma cell cultures.

Neuro-oncology advances

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Generation, characterization, and drug sensitivities of 12 patient-derived IDH1-mutant glioma cell cultures.

Neuro-oncology advances

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Neuro-oncology advances

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