A novel μ-oxo-diruthenium(III,III)-ibuprofen-(4-aminopyridine) chloride derived from the diruthenium(II,III)-ibuprofen paddlewheel metallodrug shows anticancer properties.

导出 LinkOut

翻译打印收藏纠错

作者： Samara R,Alves ^[1] ; Rodrigo L S R,Santos ^[2] ; Bárbara,Fornaciari ^[1] ; Alison,Colquhoun ^[3] ; Denise,de Oliveira Silva ^[4]

作者单位： Laboratory for Synthetic and Structural Inorganic Chemistry - Bioinorganic and Metallodrugs, Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, B2T, 05508-000 São Paulo, SP, Brazil. ^[1] Laboratory for Synthetic and Structural Inorganic Chemistry - Bioinorganic and Metallodrugs, Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, B2T, 05508-000 São Paulo, SP, Brazil; Department of Exact and Technological Sciences, State University of Santa Cruz, Rod. Jorge Amado, Km 16, 45662-900 Ilhéus, BA, Brazil. ^[2] Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, 05508-000 São Paulo, SP, Brazil. ^[3] Laboratory for Synthetic and Structural Inorganic Chemistry - Bioinorganic and Metallodrugs, Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, B2T, 05508-000 São Paulo, SP, Brazil. Electronic address: deosilva@iq.usp.br. ^[4]

关键词 4-Aminopyridine Cancer Diruthenium Ibuprofen Metallodrug Oxo-bridged compounds