换一批
换一批Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study.
作者：
Amit,Bar-Or [1]
;
Heinz,Wiendl [2]
;
Xavier,Montalban [3]
;
Enrique,Alvarez [4]
;
Maria,Davydovskaya [5]
;
Silvia R,Delgado [6]
;
Evgeniy P,Evdoshenko [7]
;
Natasa,Giedraitiene [8]
;
Katrin,Gross-Paju [9]
;
Sulev,Haldre [10]
;
Craig E,Herrman [11]
;
Guillermo,Izquierdo [12]
;
Guntis,Karelis [13]
;
Fritz,Leutmezer [14]
;
Miroslav,Mares [15]
;
Jose E,Meca-Lallana [16]
;
Dalia,Mickeviciene [17]
;
Jacqueline,Nicholas [18]
;
Derrick S,Robertson [19]
;
Denis V,Sazonov [20]
;
Kenneth,Sharlin [21]
;
Bharathy,Sundaram [22]
;
Natalia,Totolyan [23]
;
Marta,Vachova [24]
;
Martin,Valis [25]
;
Morten,Bagger [26]
;
Dieter A,Häring [27]
;
Inga,Ludwig [27]
;
Roman,Willi [27]
;
Martin,Zalesak [27]
;
Wendy,Su [27]
;
Martin,Merschhemke [28]
;
Edward J,Fox [27]
作者单位：
A Bar-Or Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street - 3 Gates Building, Philadelphia, PA 19104, USA.
[1]
Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
[2]
Department of Neurology with Institute of Translational Neurology, University of Münster, Münster, Germany.
[3]
Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Barcelona, Spain.
[4]
Department of Neurology, Rocky Mountain MS Center, University of Colorado, Aurora, CO, USA.
[5]
Pirogov Russian National Research Medical University, Moscow, Russian Federation.
[6]
MS Center and Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA.
[7]
St Petersburg Center for Multiple Sclerosis and Other Autoimmune Diseases, St Petersburg, Russian Federation.
[8]
Clinic of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
[9]
West-Tallinn Central Hospital, Tallinn, Estonia/Institute of Health Care Technology, TalTech, Tallinn, Estonia.
[10]
Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia/Neurology Clinic, Tartu University Hospital, Tartu, Estonia.
[11]
JWM Neurology, Indianapolis, IN, USA.
[12]
Multiple Sclerosis Unit, Hospital Vithas NISA Sevilla, Sevilla, Spain.
[13]
Neurology and Neurosurgery Department, Riga East University Hospital and Riga Stradins University, Riga, Latvia.
[14]
Department of Neurology, Medical University of Vienna, Vienna, Austria.
[15]
Department of Neurology, Pardubice Regional Hospital, Pardubice, Czech Republic.
[16]
Multiple Sclerosis CSUR, Department of Neurology, Virgen de la Arrixaca Clinical University Hospital-IMIB-Arrixaca, Murcia, Spain/Clinical Neuroimmunology and Multiple Sclerosis Cathedra, Universidad Católica San Antonio (UCAM), Murcia, Spain.
[17]
Lithuanian University of Health Sciences, Kaunas, Lithuania.
[18]
OhioHealth Riverside Methodist Hospital, Columbus, OH, USA.
[19]
Multiple Sclerosis Division, Department of Neurology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
[20]
Department of Clinical Trials FSBIH SDMC of FMBA of Russia, Novosibirsk, Russian Federation.
[21]
Sharlin Health and Neurology, Ozark, MO, USA.
[22]
Texas Institute for Neurological Disorders, Sherman, TX, USA.
[23]
Department of Neurology, First Pavlov State Medical University of St Petersburg, St Petersburg, Russian Federation.
[24]
Department of Neurology, Teplice Hospital, Teplice, Czech Republic.
[25]
Department of Neurology, Faculty of Medicine in Hradec Králové, Charles University in Prague and University Hospital Hradec Králové, Hradec Králové, Czech Republic.
[26]
Novartis Pharma AG, Basel, Switzerland.
[27]
Novartis Pharmaceutical Corporation, East Hanover, NJ, USA.
[28]
Central Texas Neurology Consultants PA, Round Rock, TX, USA.
[29]
主题词
抗体, 单克隆(Antibodies, Monoclonal);人类(Humans);注射, 皮下(Injections, Subcutaneous);多发性硬化(Multiple Sclerosis)
DOI
10.1177/13524585211044479
PMID
34605319
发布时间
2022-07-16
- 浏览1
Multiple sclerosis (Houndmills, Basingstoke, England)
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