The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes.

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第一作者： Laura,Del Bosque-Plata

第一单位： Laboratorio de Nutrigenética y Nutrigenómica, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.

作者： Laura,Del Bosque-Plata ^[1] ; Eduardo Pavel,Hernández-Cortés ^[1] ; Claudia,Gragnoli ^[2]

作者单位： Laboratorio de Nutrigenética y Nutrigenómica, Instituto Nacional de Medicina Genómica, Mexico City, Mexico. ^[1] Department of Medicine, Division of Endocrinology, Diabetes, and Metabolic Disease, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[2] Division of Endocrinology, Creighton University School of Medicine, Omaha, Nebraska, USA. ^[3] Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA. ^[4] Molecular Biology Laboratory, Bios Biotech Multi-Diagnostic Health Center, Rome, Italy. ^[5]

关键词 Crohn's disease TCF7L2 gene Wnt-signaling pathway cancer diabetes

主题词糖尿病, 2型(Diabetes Mellitus, Type 2);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);葡糖耐受不良(Glucose Intolerance);人类(Humans);多态性, 单核苷酸(Polymorphism, Single Nucleotide);转录因子7样2蛋白(Transcription Factor 7-Like 2 Protein)

DOI 10.1002/jcp.30581

PMID 34612510

发布时间 2022-07-31

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