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首页> Digestive diseases and sciences> Silencing GS Homeobox 2 Alleviates Gemcitabine Resistance in Pancreatic Cancer Cells by Activating SHH/GLI1 Signaling Pathway.

Silencing GS Homeobox 2 Alleviates Gemcitabine Resistance in Pancreatic Cancer Cells by Activating SHH/GLI1 Signaling Pathway.

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作者： Lu,Zhuang ^[1] ; Yao,Yao ^[2] ; Lisi,Peng ^[1] ; Fang,Cui ^[3] ; Cui,Chen ^[1] ; Yang,Zhang ^[1] ; Liqi,Sun ^[1] ; Qihong,Yu ^[1] ; Kun,Lin ^[1]

作者单位： Department of Gastroenterology, Changhai Hospital, Navy Military Medical University, 168 Changhai Road, Shanghai, 200433, China. ^[1] Shanghai Hongkou District Jiaxing Road Subdistrict Community Healthcare Service Center, 1 Hongguan Road, Shanghai, 200086, China. ^[2] Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200030, China. ^[3] Department of Gastroenterology, Changhai Hospital, Navy Military Medical University, 168 Changhai Road, Shanghai, 200433, China. drlinkun@163.com. ^[4] Department of Gastroenterology, Zhongnan Hospital, Wuhan University, 169 Donghu Road, Wuhan, 430071, China. drlinkun@163.com. ^[5]

关键词 GS homeobox 2 (GSH2)Gemcitabine Glioma-associated oncogene homolog 1 (GLI1)Pancreatic cancer Sonic hedgehog (SHH)

主题词动物(Animals);癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);脱氧胞苷(Deoxycytidine);基因沉默(Gene Silencing);基因, 同源盒(Genes, Homeobox);猬蛋白质类(Hedgehog Proteins);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);小鼠(Mice);胰腺肿瘤(Pancreatic Neoplasms);信号传导(Signal Transduction)

DOI 10.1007/s10620-021-07262-1

PMID 34623580

发布时间 2023-12-13

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Digestive diseases and sciences

Digestive diseases and sciences

2022年67卷8期

3773-3782页

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