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首页> Cancer science> Aberrant expression of MYD88 via RNA-controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer.

Aberrant expression of MYD88 via RNA-controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer.

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作者： Masumi,Tsuda ^[1] ; Misa,Noguchi ^[2] ; Tsuyoshi,Kurai ^[3] ; Yuji,Ichihashi ^[1] ; Koki,Ise ^[4] ; Lei,Wang ^[1] ; Yusuke,Ishida ^[1] ; Mishie,Tanino ^[1] ; Satoshi,Hirano ^[1] ; Masahiro,Asaka ^[2] ; Shinya,Tanaka ^[3]

作者单位： Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, Sapporo, Japan. ^[1] Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan. ^[2] Global Station for Soft Matter, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Japan. ^[3] Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, Sapporo, Japan. ^[4] Department of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan. ^[5] Health Sciences University of Hokkaido, Tobetsu, Japan. ^[6]

关键词 CNOT4 EXOSC3 MYD88 RNA control colon cancer preventive medicine

主题词成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);细胞系(Cell Line);结肠肿瘤(Colonic Neoplasms);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HEK293细胞(HEK293 Cells);人类(Humans);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);髓样分化因子88(Myeloid Differentiation Factor 88);预后(Prognosis);RNA结合蛋白质类(RNA-Binding Proteins);信号传导(Signal Transduction);转录因子(Transcription Factors);增量调节(Up-Regulation)

DOI 10.1111/cas.15157

PMID 34626022

发布时间 2021-12-18

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Cancer science

Cancer science

2021年112卷12期

5100-5113页

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