Design, synthesis and biological evaluation of novel o-aminobenzamide derivatives as potential anti-gastric cancer agents in vitro and in vivo.-论文-万方医学网

作者： Yiyue,Feng ^[1] ; Yingmei,Lu ^[1] ; Junfang,Li ^[1] ; Honghua,Zhang ^[1] ; Zhao,Li ^[1] ; Hanzhong,Feng ^[2] ; Xuemei,Deng ^[1] ; Dan,Liu ^[1] ; Tao,Shi ^[1] ; Weifan,Jiang ^[3] ; Yongxing,He ^[4] ; Jian,Zhang ^[5] ; Zhen,Wang ^[6]

作者单位： School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ^[1] Ministry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China. ^[2] School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China. ^[3] Ministry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China. Electronic address: heyx@lzu.edu.cn. ^[4] Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200025, China. Electronic address: jian.zhang@sjtu.edu.cn. ^[5] School of Pharmacy, Lanzhou University, Lanzhou, 730000, China; School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China. Electronic address: zhenw@lzu.edu.cn. ^[6]

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);苯甲酰胺类(Benzamides);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);女(雌)性(Female);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交系(Mice, Inbred Strains);小鼠, 裸(Mice, Nude);分子结构(Molecular Structure);肿瘤, 实验性(Neoplasms, Experimental);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);构效关系(Structure-Activity Relationship);肿瘤细胞, 培养的(Tumor Cells, Cultured)

DOI 10.1016/j.ejmech.2021.113888

PMID 34628244

发布时间 2022-01-24

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Design, synthesis and biological evaluation of novel o-aminobenzamide derivatives as potential anti-gastric cancer agents in vitro and in vivo.

European journal of medicinal chemistry

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European journal of medicinal chemistry

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Design, synthesis and biological evaluation of novel o-aminobenzamide derivatives as potential anti-gastric cancer agents in vitro and in vivo.

European journal of medicinal chemistry

相似文献

European journal of medicinal chemistry

相关期刊

检索历史清除