首页> Translational stroke research> Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner.

Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner.

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第一作者： Ole,Heinisch

第一单位： Department of Neurology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.

作者： Ole,Heinisch ^[1] ; Thomas,Zeyen ^[2] ; Tobias,Goldmann ^[3] ; Marco,Prinz ^[4] ; Michael,Huber ^[5] ; Jennifer,Jung ^[1] ; Eren,Arik ^[1] ; Shahin,Habib ^[6] ; Alexander,Slowik ^[7] ; Arno,Reich ^[1] ; Jörg B,Schulz ^[8] ; Pardes,Habib ^[9]

作者单位： Department of Neurology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany. ^[1] Department of Neurology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.;Department of Neurology, University Hospital of Bonn, Bonn, Germany. ^[2] Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany. ^[3] Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.;Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.;Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany. ^[4] Institute of Biochemistry and Molecular Immunology, Medical Faculty, RWTH Aachen University, Aachen, Germany. ^[5] Medical Biochemistry, Department of Biochemistry, University of Leicester, Leicester, UK. ^[6] Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany. ^[7] Department of Neurology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.;JARA-BRAIN Institute of Molecular Neuroscience and Neuroimaging, Forschungszentrum Jülich GmbH and RWTH Aachen University, Aachen, Germany. ^[8] Department of Neurology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany. phabib@ukaachen.de.;Institute of Biochemistry and Molecular Immunology, Medical Faculty, RWTH Aachen University, Aachen, Germany. phabib@ukaachen.de.;JARA-BRAIN Institute of Molecular Neuroscience and Neuroimaging, Forschungszentrum Jülich GmbH and RWTH Aachen University, Aachen, Germany. phabib@ukaachen.de. ^[9]

关键词 EPO Inflammasomes Microglia Neuroinflammation Stroke TAK1