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首页> Mitochondrion> In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells.

In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells.

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作者： Nina,Krako Jakovljevic ^[1] ; Kasja,Pavlovic ^[1] ; Tijana,Zujovic ^[1] ; Tamara,Kravic-Stevovic ^[2] ; Aleksandra,Jotic ^[1] ; Ivanka,Markovic ^[3] ; Nebojsa M,Lalic ^[4]

作者单位： Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Dr Subotica 13, 11000 Belgrade, Serbia. ^[1] Institute of Histology and Embryology, Faculty of Medicine, University of Belgrade, Visegradska 26, 11000 Belgrade, Serbia. ^[2] Institute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, Pasterova 2, 11000 Belgrade, Serbia. ^[3] Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Dr Subotica 13, 11000 Belgrade, Serbia. Electronic address: nebojsa.lalic@med.bg.ac.rs. ^[4]

关键词 Cell models Hepatocytes Insulin resistance Mitochondria Myocytes Respiration

主题词动物(Animals);细胞系(Cell Line);细胞存活(Cell Survival);基因表达调控(Gene Expression Regulation);人类(Humans);胰岛素(Insulin);胰岛素抗药性(Insulin Resistance);小鼠(Mice);线粒体, 肝(Mitochondria, Liver);线粒体, 肌(Mitochondria, Muscle);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);活性氧(Reactive Oxygen Species);信号传导(Signal Transduction)

DOI 10.1016/j.mito.2021.10.001

PMID 34634496

发布时间 2022-03-21

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