Kinetic Modeling to Accelerate the Development of Nucleic Acid Formulations.

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作者： Esther H,Roh ^[1] ; Thomas H,Epps ^[1] ; Millicent O,Sullivan ^[2]

作者单位： Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States. ^[1] Center for Research in Soft matter and Polymers (CRiSP), University of Delaware, Newark, Delaware 19716, United States. ^[2] Department of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States. ^[3] Department of Biomedical Engineering, University of Delaware, Newark, Delaware 19716, United States. ^[4]

关键词 gene delivery kinetic model nanoparticle nucleic acid therapeutics siRNA

主题词动物(Animals);动力学(Kinetics);核酸类(Nucleic Acids);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);回顾性研究(Retrospective Studies)

DOI 10.1021/acsnano.1c04555

PMID 34636541

发布时间 2022-10-13

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