换一批
换一批Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity.
作者：
主题词
投药, 口服(Administration, Oral);动物(Animals);抗肿瘤药(Antineoplastic Agents);生物利用度(Biological Availability);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物发现(Drug Discovery);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);女(雌)性(Female);人类(Humans);吲哚类(Indoles);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);分子结构(Molecular Structure);肿瘤, 实验性(Neoplasms, Experimental);核受体亚家族1, F组, 成员3(Nuclear Receptor Subfamily 1, Group F, Member 3);构效关系(Structure-Activity Relationship)
DOI
10.1021/acs.jmedchem.1c00828
PMID
34643383
发布时间
2021-12-14
- 浏览1
Journal of medicinal chemistry
14983-14996页
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