Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner.

导出 OA

翻译打印收藏纠错

第一作者： Xiang-Shu,Cheng

第一单位： Department of Neurology, Translational Medicine Center, Huaihe Hospital Affiliated to Henan University, Kaifeng 475000, Henan, China.

作者： Xiang-Shu,Cheng ^[1] ; Fang-Xiao,Shi ^[2] ; Kun-Peng,Zhao ^[3] ; Wang,Lin ^[2] ; Xiao-Ying,Li ^[2] ; Jun,Zhang ^[4] ; Yao-Yao,Bu ^[2] ; Rui,Zhu ^[1] ; Xiao-Hong,Li ^[1] ; Dong-Xiao,Duan ^[1] ; Xin-Ying,Ji ^[2] ; Jian-She,Wei ^[2] ; Jian-Zhi,Wang ^[2] ; Jin,Du ^[5] ; Xin-Wen,Zhou ^[6]

作者单位： Department of Neurology, Translational Medicine Center, Huaihe Hospital Affiliated to Henan University, Kaifeng 475000, Henan, China. ^[1] Department of Pathophysiology, Key Laboratory of Neurological Disease of National Education Ministry and Hubei Province, Institute for Brain Research, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China. ^[2] Brain Research Laboratory, Henan University, Kaifeng 475004, Henan, China. ^[3] Department of Psychiatry, Henan Key Lab of Biological Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang 453002, Henan, China. ^[4] Department of Physiology, Basic Medical College, Zhengzhou University, Zhengzhou 450001, Henan, China. ^[5] Department of Microbiology, Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, Henan, China. ^[6] Department of Respiratory, Huaihe Hospital Affiliated to Henan University, Kaifeng 475000, Henan, China. ^[7]

关键词 ADAM10 AMPK Alzheimer disease amyloid-β nicotinamide mononucleotide adenylyltransferase 2