FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway.

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第一作者： Yanhui,Li

第一单位： Clinical School of Medicine, Hebei University of Engineering, Handan, 056000, Hebei, China.

作者： Yanhui,Li ^[1] ; Yue,Xiong ^[1] ; Zhen,Wang ^[2] ; Jianjun,Han ^[3] ; Sufang,Shi ^[3] ; Jinglan,He ^[4] ; Na,Shen ^[5] ; Wenjuan,Wu ^[3] ; Rui,Wang ^[3] ; Weiwei,Lv ^[3] ; Yajun,Deng ^[3] ; Weiguang,Liu ^[6]

作者单位： Clinical School of Medicine, Hebei University of Engineering, Handan, 056000, Hebei, China. ^[1] Department of Laboratory Medicine, Medical College, Hebei University of Engineering, Handan, 056000, Hebei, China. ^[2] Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ^[3] Department of Orthopedic Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ^[4] Science and Education Division, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. ^[5] Department of Breast Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, 056000, Hebei, China. liuweiguang@hebeu.edu.cn. ^[6]

关键词 Breast cancer Chemoresistance ELAVL1 FAM49B Metastasis Proliferation Rab10 TLR4

DOI 10.1186/s12935-021-02244-9

PMID 34645466

发布时间 2021-10-22

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