换一批
换一批Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR.
第一作者：
Jun,Yan
第一单位：
The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510720, China; Department of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);查耳酮类(Chalcones);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);人类(Humans);吲哚类(Indoles);肝肿瘤, 实验性(Liver Neoplasms, Experimental);男(雄)性(Male);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);分子结构(Molecular Structure);构效关系(Structure-Activity Relationship);硫氧还蛋白二硫化物还原酶(Thioredoxin-Disulfide Reductase);微管蛋白(Tubulin);微管蛋白调节因子(Tubulin Modulators)
DOI
10.1016/j.ejmech.2021.113897
PMID
34649064
发布时间
2022-01-24
- 浏览0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
